Maria Cecilia Hospital, GVM Care & Research, Cotignola, Italy
Review
State of The Art in Clinical Management of Channelopathies and Risk of
Sudden Cardiac Death
Author(s): Malagù M*, Balla C, Gualandi F, Vitali F, Selvatici R, Ferlini A, Zaraket F, Del Franco A, Cimaglia P, Squeri A, Ferrari R and Bertini M
Major arrhythmias and sudden cardiac death in young and apparently healthy people are usually the first
manifestation of cardiac channelopathies (CC). CC include long QT syndrome, short QT syndrome, Brugada
syndrome and catecholaminergic polymorphic ventricular tachycardia. Identification and proper management of
these diseases is a challenge for the clinical cardiologists, which could benefit from collaboration with geneticists and
other physicians due to relevant genetic, molecular, biologic and psychologic implications. Medical awareness of
these issues is growing fast as clinical research provides continue update. In this paper, we provide a comprehensive
review of CC. The genes associated with CC and their relative role are here illustrated and summarized.. Read More»
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