Division of Animal Biochemistry, Institute of ICAR-National Dairy Research, Near Jewels Hotel, Dyal Singh Colony, Karnal, Haryana 132001, India
Review Article
Metabolic Syndrome: A Comprehensive Review on Understanding Pathophysiology, Clinical Implications and Different Management Strategies
Author(s): Usha Devi and Suman Kapila*
Metabolic syndrome, a multifaceted cluster of conditions encompassing insulin resistance, central obesity, dyslipidemia, and inflammation, poses
a significant global health challenge. This comprehensive review synthesizes current knowledge on the pathophysiology, clinical implications, and
management strategies associated with metabolic syndrome. In exploring the intricate interplay of insulin resistance, obesity-related inflammation,
and hormonal factors, we elucidate the mechanisms underlying this syndrome. Clinical implications delve into the heightened risks of cardiovascular
disease, type 2 diabetes, non-alcoholic fatty liver disease, and renal dysfunction, emphasizing the syndrome's profound impact on morbidity and
mortality. The review critically examines lifestyle modifications, pharmacological interventions, and weight management strategies, underscoring
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DOI:
10.37421/2167-0943.2024.13.350
Journal of Metabolic Syndrome received 48 citations as per Google Scholar report