Journal of Clinical Case Reports

DFCPS Postgraduate Trainee, Dow University of Health Sciences, Karachi, Pakistan

Publications

• Case Report   
  Thinking of Rare Bleeding Disorders in the Emergency Room: A Diagnosis of Glanzmann Thrombasthenia in a Pakistani Child
  Author(s): Salma Mainosh, Ayesha Akbar Khalid*, Mushtaq Ahmed and Syeda Shaheera Hashmi Riaz
  
  Introduction: Glanzmann thrombasthenia is a rare inherited bleeding disorder, with a global prevalence of about one in one million. It is an autosomal recessive condition characterised by episodes of mucocutaneous bleeding. A defect in the membrane protein results in a defective platelet aggregation. Case presentation: A fifteen-month-old female child presented to the emergency department with nosebleed for the last two days. The patient had two similar episodes of epistaxis in previous few months which were managed at home. There was an accompanying complaint of easy bruising since birth. After emergency management and anterior nasal packing, extensive blood tests were ordered to determine the cause for recurrent haemorrhages. Platelet aggregation study concluded a diagnosis of Glanzmann thrombasthenia and the patient was tr.. Read More»
  

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