Cancer Science & Therapy

Department of cancer, OptoVibronex, LLC. Ben Franklin Tech Ventures, Bethlehem, USA

Publications

• Research Article   
  Use of Pixel Intensity Measurements Derived from OCT Images to Differentiate Between Seborrheic Keratosis and Melanomas: A Pilot Study
  Author(s): Frederick H. Silver*, Tanmay Deshmukh, Aanal Patel and Hari Nadamint
  
  Differentiating Seborrheic Keratosis (SK) from melanoma can be difficult based on visual observations and dermoscopy since both are pigmented lesions. While SK is considered a benign lesion that is localized, in contrast melanoma can spread to other tissues and lead to death if it metastasizes. Therefore, it is important to be able to noninvasively differentiate between SK and melanoma to limit the number of unnecessary biopsies performed. We have measured the pixel intensity of Optical Coherence Tomography (OCT) images of normal skin, SK, and melanoma by breaking OCT images into low (green), medium (blue) and high (red) pixel intensity vs. depth images. Normal skin and SK are characterized by higher green scale pixel intensity vs. depth plots while melanoma has a lower green scale pixel intensity vs. depth plot. Melanoma also has lower red sc.. Read More»
  DOI: 10.37421/1948-5956.2024.16.680

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