Department of Pathology, Vietnam National Children’s Hospital, 14 Ly Tu Trong, Ben Nghe, District 1, Ho Chi Minh City, Vietnam
Case Report
A Case of Polyarteritis Nodosa with Positive Anti-phospholipid Antibodies Presenting with Multifocal Myositis
Author(s): Ha Thu Thi Nguyen*, Chi Quynh Le, Thach Ngoc Hoang, Giang Dinh Nguyen and Anh Van Thi Nguyen
Background: Poly Arteritis Nodosa (PAN) is a rarely necrotizing vasculitis in childhood and is characterized by the inflammation of small and medium vessels affecting multiple organs. Although the presence of Anti Phosphor Lipid (APL) antibodies in PAN has been documented, there is limited data on the prevalence and understanding of pathogenesis and management for such co-incidence.
Case study: We herein reported that a 7-year-old boy without significant past medical history presented initially with high-grade fever, painful subcutaneous nodules, and ankle arthritis for 14 days prior to hospitalization. Biological findings revealed increased acute inflammatory biomarkers and no evidence of infection. The deep skin biopsy taken from the subcutaneous nodule proved leukocytoclastic medium-sized vasculitis suggestive of the PAN diagnosis. He eve.. Read More»
DOI:
10.37421/2165-7920.2024.14.1597
Journal of Clinical Case Reports received 1345 citations as per Google Scholar report