Department of Pathology, Institut Universitaire du Cancer de Toulouse (IUCT) Oncopole, 31100 Toulouse, France
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SOCS1: Shedding Light on HPV-Associated Head and Neck Cancers
Author(s): Trine Weist*
HPV (Human Papillomavirus) infection has emerged as a significant risk factor for the development of Head and Neck Squamous Cell Carcinomas
(HNSCC). Identifying reliable biomarkers that can accurately predict HPV infection and assess prognosis is crucial for effective management
of these cancers. This study focuses on the role of Suppressor of Cytokine Signaling 1 (SOCS1) as a promising biomarker in HPV-associated
HNSCC. SOCS1 is a key regulator of various cellular processes, including immune response, inflammation, and cell proliferation. Recent research
has highlighted its potential involvement in HPV infection and subsequent carcinogenesis in the head and neck region. Aberrant SOCS1 expression
has been observed in HPV-positive HNSCC samples, suggesting its possible role as a diagnostic and prognostic marker. This comprehensive
analysis explores the associati.. Read More»
DOI:
10.37421/2155-9929.2023.14.578
Molecular Biomarkers & Diagnosis received 2054 citations as per Google Scholar report