Department of Biochemistry, Faculty of Science, University of Dschang, Cameroon
Research
Stimulation of Phagocytosis in Alveolar Macrophages and Resistance against Infection in Mice by the Aqueous Extract of Rhizomes of Aframomum danielli, Schum (zingiberaceae)
Author(s): Oumar Mahamat*, Tume Christopher, Guessom Oulianovie and Kamanyi Albert
Background: Alveolar Macrophages (AMs) play important role in preservation of lungs from infectious diseases development through a series of activities including phagocytosis. The present study examined the effects of aqueous extract of Aframomum danielli rhizomes on the AMs functions.
Methods: Extract was investigated for microbe’s ingestion, bacteria killing and reactive oxygen and nitrogen species production in alveolar macrophages. Extract was investigated for repository, suppressive and curative treatments of S. aureus infection in mice.
Results: The extract of Aframomum danielli augmented (approximately threefold) the ingestion of Candida albicans by phagocytes. Furthermore, extract concentrationdependently increased the killing ability of S. aureus of mice A.. Read More»
DOI:
10.37421/2327-5162.2020.9.294
Alternative & Integrative Medicine received 476 citations as per Google Scholar report