Journal of Oncology Translational Research

Department of Pharmacology and Toxicology, Nnamdi Azikiwe University, Awka, Nigeria

Publications

• Research Article   
  Evaluation of Immune Complexomes and Possible Pathological Influences at Various Stages of Breast Cancer
  Author(s): Michael Chukwudi Ezeani*, Ujuamala Uloma Ezeani, Henry Chima Opkara, Rosemary Adamma Analike, Emeka Callistus Onyeka Izuchukwu, Bright Chukwuebuka Unaeze and Ngozichukwu Gertrude Uzoewulu
  
  Staging of breast cancer is important in the reading of cancer progression and level of treatment required. Certain underlying factors may be determinant and consequent to prognostic values at various stages. These underlying factors are considered to include circulating immune complexes which has the capability to mediate molecular expression and could give insight into possible progressive remission developments at various stages of Breast cancer. Methods: We recruited 50 female participants including 10 with benign tumour, 15 apparently healthy participants and 25 with malignant tumour and at stages: 2 (No.6); 3b (No.8); 3c (No.7) and 4 (No.4). Prospective observational analytical study was conducted to identify changes in certain inflammatory molecules, DNA oxidation and sex hormonal molecules in different stages, with respect to increa.. Read More»
  DOI: 10.37421/2476-2261.2023.9.226

  Abstract HTML PDF