Journal of Genetics and DNA Research

Department of Medical Genetics, University of Pisa, Pisa, Italy

Publications

• Mini Review   
  DNA Repair: The Intricate Molecular Dance Safeguarding our Genetic Blueprint
  Author(s): Valentina Tozzini*
  
  DNA repair mechanisms play a crucial role in maintaining the integrity of our genetic blueprint, protecting it from various forms of damage. This intricate molecular dance involves a network of intricate pathways and processes that work together to identify and rectify DNA lesions, ensuring faithful transmission of genetic information from one generation to the next. Understanding the intricacies of DNA repair is essential for comprehending the etiology of numerous genetic disorders, as well as the development of effective therapeutic strategies for diseases linked to defective repair systems. This review explores the multifaceted nature of DNA repair, highlighting the key players and mechanisms involved in the detection and repair of various DNA lesions, including base modifications, strand breaks, and cross-links. The interplay between different repair pathwa.. Read More»
  DOI: 10.37421/2684-6039.2023.7.156

  Abstract HTML PDF