Immunochemistry & Immunopathology

Clinical Affairs, AliveDx, Eysins, Switzerland

Publications

• Research Article   
  Performance Characteristics of a Novel, Fully Automated Planar Microarray Immunoassay for the Detection of Antibodies against Centromere Protein B
  Author(s): Pascale Ghillani-Dalbin, Christel Daubrosse, Valrie Mercier, Rocio Pasion-Galvan, Gerber Gomez*, Daphne Bijlsma, Ewa Lukasik, Valeria Botti, Emmanuel Moreau, Christine C. Ginocchio, Michael Hausmann and Makoto Miyara
  
  Introduction: Autoantibody testing, including against Centromere Proteins (CENP), is important in the identification of autoimmune diseases. Test methods may be manual, slow, labor-intensive and/or fragmented. Development of highly automated tools is needed. We aimed to evaluate the performance of MosaiQ® CENP-B (CENP-B-MA), a planar microarray immunoassay designed for use with the fully automated, continuous random access, high-throughput MosaiQ System, for the qualitative serological detection of anti-CENP-B autoantibodies (ACA-B) as an aid in the diagnosis of systemic sclerosis. Methods: A comparator study was performed at Hôpital Pitié-Salpêtrière, Paris, France using anonymized serum samples, characterized as ACA-B non-reactive or reactive with CE-marked devices. Reproducibility and repeat.. Read More»
  DOI: 10.37421/2469-9756.2023.9.207

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