Department of Dermatology, Regenerative Processing Plant, Palm Harbor, Florida, USA
Perspective
The Impact of Cigarette Smoking on the Therapeutic Potential of Mesenchymal Stem Cells
Author(s): Veena Madhuri*
Cigarette smoking is a global health concern associated with a multitude of adverse health effects, including increased susceptibility to various
diseases and reduced overall life expectancy. Recent research has uncovered a novel dimension to the detrimental consequences of smoking
by examining its impact on the therapeutic potential of mesenchymal stem cells. MSCs have gained prominence in regenerative medicine due
to their regenerative and immunomodulatory properties. This review explores the intricate relationship between cigarette smoking and MSCs,
shedding light on how smoking may compromise the effectiveness of MSC-based therapies. We discuss the molecular mechanisms underlying
this phenomenon, encompassing alterations in MSC proliferation, differentiation and immunomodulation in the presence of cigarette smoke
constituents. Moreover, we delve into the po.. Read More»
DOI:
10.37421/2684-494X.2023.8.79
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