Department of Pulmonary/Critical Care Medicine, Yale New Haven Health-Bridgeport Hospital, Bridgeport, Connecticut, USA
Case Report
The Bugs were not to Blame; Granulomatosis with Polyangiitis Presenting as a Renal Mass
Author(s): Kwabena Sefah Nketiah Sarpong*, Marat Kribis, Vesna Buntak and Christine Minerowicz
Granulomatosis with Polyangiitis (GPA) is an anti-neutrophil cytoplasm antibody (ANCA) associated vasculitis that rarely presents as a solitary renal mass. We present
a 57-year-old male who presented with abdominal pain and was found to have a complex right renal lesion on abdominal imaging. He later developed fevers, hypoxic
respiratory failure and acute kidney injury. Chest imaging showed confluent consolidative changes in the mid to lower lung zones. He was started on antibiotics but continued
to worsen. He was noted to have diffuse alveolar hemorrhage on bronchoscopy with autoantibodies to proteinase-3 (PR-3) returning positive. He was started on rituximab
and steroids with dramatic improvement. Kidney biopsy revealed crescentic and necrotizing glomerulonephritis associated with ANCA-associated vasculitis. GPA presenting
as a renal mass presents a diagnostic ch.. Read More»
DOI:
10.37421/2471-9544.2022.8.160
Journal of Vasculitis received 83 citations as per Google Scholar report