Cancer Science & Therapy

Department of Gastroenterology, National Institute of Gastroenterology, Bari, Italy

Publications

• Research Article   
  Liver Inflammation Parameters in Relation to Survival in Patients with Hepatocellular Carcinoma Tumor of differing Sizes
  Author(s): Brian Carr*, Vito Guerra, Ümit Karaoğullarından, Hikmet Akkiz, Volkan Ince, Burak Isik and Sezai Yilmaz
  
  Introduction: Survival in patients with Hepatocellular Carcinoma (HCC) has been previously found to be worse with increase in tumor size, but also with increase in inflammation. To examine these issues separately, we aimed to study the influences on survival of various liver inflammation parameters in the whole cohort, and separately in patients with HCCs of defined Maximum Tumor Diameter (MTD). Methods: A prospectively collected large database of Turkish HCC patients with documented survival was interrogated. Patients had baseline liver function tests and CT scans for tumor characteristics. Liver function and inflammation parameters included blood tests for levels of albumin, AST, GGT, ALKP, CRP, ESR and WBC. Results: Survival was worse for patients with larger HCCs, including those with low or high serum AFP level.. Read More»
  

  Abstract PDF