Department of Chronic Disease Epidemiology, University Hospital Tübingen, 72076 Tübingen, Germany
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Emerging Biomarkers for Early Detection of Hepatocellular Carcinoma
Author(s): William Jennifer*
Hepatocellular carcinoma is one of the most prevalent types of liver cancer, with a high mortality rate worldwide. Early detection of HCC is
crucial for effective treatment and improved patient outcomes. While conventional diagnostic methods like imaging and biopsy remain primary
tools, emerging biomarkers offer promising avenues for early detection, enabling timely intervention. This article explores recent advancements
in biomarkers for the early detection of HCC. Alpha-Fetoprotein (AFP) has long been utilized as a biomarker for HCC screening. However, its
sensitivity and specificity are suboptimal, leading to the exploration of novel biomarkers to complement AFP in early detection efforts. Recent
studies have investigated AFP-L3 and des-gamma-carboxy prothrombin isoforms of AFP, which have shown improved performance in detecting
early-stage HCC. MicroRNAs ar.. Read More»
DOI:
10.37421/2573-4563.2024.8.260
Hepatology and Pancreatic Science received 34 citations as per Google Scholar report