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Molecular and Genetic Medicine

ISSN: 1747-0862

Open Access

Winter K

Washington University in St. Louis, Department of Medicine, St Louis, MO, USA

Publications
  • Research Article   
    Usefulness and Applicability of Next Generation Sequencing in Neuroendocrine Neoplasms
    Author(s): Manyanont S*, Winter K and Trikalinos NA

    Background: Neuroendocrine neoplasms (NENs) are rare tumors that can arise anywhere in the body and treatment options are limited due to their rarity. Knowledge of their mutational status might allow for tumor agnostic treatments, suggest a familial component or aid in enrollment in clinical trials, especially in the metastatic setting. Objective: We aimed to evaluate the clinical relevance of results from next generation sequencing (NGS) in NEN patients and determine their applicability to patient management. Patients and methods: Eligible NEN patients on an institutional, IRB approved protocol, who had NGS as standard of care and were treated in the past 24 months, were included. Tumors were categorized by location and histologic grade. We explored the actual and theoretical eligibility for tumor agnostic treatments .. Read More»
    DOI: 10.37421/1747-0862.2020.14.S2

    Abstract HTML PDF

Google Scholar citation report
Citations: 3919

Molecular and Genetic Medicine received 3919 citations as per Google Scholar report

Molecular and Genetic Medicine peer review process verified at publons

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