Reports in Thyroid Research

Department of Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, P.R. China

Publications

• Mini Review   
  Location of RAS Change by Pyro Sequencing in Thyroid Cytology Tests
  Author(s): Xiaohua Zhang*
  
  Fine-needle goal cytology (FNAC) is the essential means to recognize harmless from dangerous thyroid knobs. Nonetheless, adjunctive demonstrative tests are required as 20-40% of FNAC are uncertain. RAS transformations have been depicted in separated thyroid disease and they could be utilized as cancer markers. Nonetheless, their commonness differs broadly among studies, likely because of the identification strategies utilized. We researched whether the pyro sequencing technique can be applied to identify NRAS and KRAS transformations in thyroid suctions A sum of 37 thyroid suctions, including harmless hyperplastic knobs (HBN, N = 16) and follicular thyroid carcinomas (FTC, N = 21) were broke down for the presence of NRAS61 and KRAS13 mutations A RAS change was viewed as in 31% and 62% of BN and FTC separately. Most examples showed a level of changed alleles lower than half (middle = 3.. Read More»
  DOI: 10.37421/2684-4273.2022.07.20

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