Dr, Department of Pathology, Peoples Hospital of Zhengzhou University, Zhengzhou, China
Case Report
Primary Cutaneous Extranodal NK/T-Cell Lymphoma, Nasal Type, with Extensive Skin Lesions and Immune Cell Shift.
Author(s): Xie Hongjian*
Primary Cutaneous Extranodal Natural Killer (NK)/T-cell Lymphoma, nasal type (PC-ENKTL), is a rare entity of malignancies of NK cells or cytotoxic T cells, characterized by an association with Epstein-Barr virus (EBV) infection. Despite its aggressive behavior, PC-ENKTL is mostly found as a localized disease. Data regarding PC-ENKTL with generalized skin lesions have only rarely been characterized in clinical studies so far. We present a case of PC-ENKTL, nasal type, in a 38-year–old female with a history of disseminated cutaneous plaques, ulcers and painful nodules that originated in her right leg skin as a small raised papule and expanded quickly over the entire body, ranging in diameter from 1 cm to 6 cm. The patient did not show any involvement of other sites except skin. Histologic, immunophenotypic, genetic and clinical features consistent with the diagnosis of primary cut.. Read More»
DOI:
10.37421/ 2165-7831.2022.12.284
Journal of Blood & Lymph received 443 citations as per Google Scholar report