GET THE APP

..

Journal of Infectious Diseases and Medicine

ISSN: 2576-1420

Open Access

Yang Zhang

Department of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150001, China

Publications
  • Perspective   
    Acinus Allergen 2 Insufficiency Persuade Nimble Responses and Regulate Rapacious Deltacoronavirus Infection
    Author(s): Yang Zhang*

    Porcine deltacoronavirus (PDCoV) is a lately observed enteropathogenic coronavirus and has prompted substantial monetary influences on the pork industry. Although research has partly uncovered the molecular mechanism of PDCoV–host interaction, it requires in addition research. In this study, we explored the roles of Stromal Antigen two (STAG2) in PDCoV infection. We located that STAG2-deficient cells inhibited contamination with vesicular stomatitis virus (VSV) and PDCoV, whereas restoration of STAG2 expression in STAG2-depleted (STAG2−/−) IPEC-J2 cells line restored PDCoV infection, suggesting that STAG2 is concerned in the PDCoV replication. Furthermore, we located that STAG2 deficiency consequences in strong interferon (IFN) expression. Subsequently, we observed that STAG2 deficiency outcomes in the activation of JAK-STAT signaling and the .. Read More»
    DOI: 10.37421/2576-1420.2022.7.239

    Abstract HTML PDF

Google Scholar citation report
Citations: 59

Journal of Infectious Diseases and Medicine received 59 citations as per Google Scholar report

Journal of Infectious Diseases and Medicine peer review process verified at publons

Indexed In

 
arrow_upward arrow_upward