Department of Horticulture, Gansu Agriculture University, Lanzhou 730070, China
Mini Review
Supplemental Micronutrients, Tight Junctions and Epithelial Barrier Function: A Narrative Review
Author(s): Yavuz Hord*
This narrative review examines the role of supplemental micronutrients in modulating tight junctions and epithelial barrier function. Tight junctions
are critical components of epithelial barriers in various tissues, including the gastrointestinal tract, respiratory system and skin, regulating the
paracellular transport of ions, solutes and immune cells. Emerging evidence suggests that micronutrients, such as vitamins (e.g., vitamin D,
vitamin A and vitamin C), minerals (e.g., zinc, selenium) and polyphenols, play crucial roles in maintaining the integrity and function of tight
junctions. This review explores the mechanisms through which micronutrients influence tight junction dynamics, barrier integrity and immune
responses, highlighting their potential therapeutic implications in conditions characterized by epithelial barrier dysfunction, such as inflammatory
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DOI:
10.37421/2376-1318.2024.13.305
Vitamins & Minerals received 790 citations as per Google Scholar report