Department of Clinical Research, University of Alexandria, Alexandria Governorate, Egypt
Mini Review
An Overview of Immune Checkpoint Inhibitors in the Treatment of Gynecological Cancer
Author(s): Youssef El-Sayed*
Immune Checkpoint Inhibitors (ICIs) have emerged as a groundbreaking therapeutic modality in the field of oncology, offering new hope for patients
with various types of cancer, including gynecological malignancies. These inhibitors target immune checkpoints, key regulators of the immune
system, to enhance the body's antitumor response. This article provides an extensive overview of the role of ICIs in the treatment of gynecological
cancers, including cervical, ovarian, and endometrial cancers. It discusses the mechanism of action, clinical efficacy, ongoing research, and
future prospects of these therapies. The literature review highlights key clinical trials and studies that have shaped the current understanding of
ICIs in gynecological oncology. Furthermore, the discussion section addresses the challenges, limitations, and potential strategies to overcome
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DOI:
10.37421/2577-0535.2024.9.254
Journal of Cancer Clinical Trials received 95 citations as per Google Scholar report