Department of Oral Biology, Universitas Indonesia, Jakarta, Indonesia
Mini Review
A Systematic Review of the Proteomics Approach for Biomarkers and Periodontitis Diagnosis
Author(s): Yuniarti Soeroso*
We wanted to see how accurate salivary matrix metalloproteinases (MMP)-8 and -9, as well as tissue inhibitor of metalloproteinase (TIMP)-1, were
at diagnosing periodontitis and differentiating periodontitis stages 1 to S3. This was a case-control study involving patients with periodontitis S1 to
S3 and healthy periodontia. Saliva was collected, and clinical parameters such as plaque index, bleeding on probing, probing pocket depth, and
clinical attachment level were recorded. Radiography was used to confirm the diagnosis by measuring the alveolar bone level. An enzyme-linked
immunosorbent assay was used to measure salivary biomarkers. A total of 45 patients and 18 healthy subjects served as controls... Read More»
DOI:
10.37421/2155-9929.2022.13.551
Molecular Biomarkers & Diagnosis received 2054 citations as per Google Scholar report