Metabolomics:Open Access

International Conference and Exhibition on Metabolomics & Systems Biology

20-22 February 2012 San Francisco Airport Marriott Waterfront, USA

Scientific Tracks Abstracts

• Metabolic profile of endocrine resistance

  Robert Clarke

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• Gene Expression Profiling of the cancer chemotherapeutic agent, Cisplatin, compared with its ineffective Isomer, Transplatin

  Vincent Murray and Anne M. Galea

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• Gene expression profiling of differentiating hematopoietic stem cells identifies transcriptional dysregulation in haematological malignancies

  Wolf-K. Hofmann

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• Transcriptional module discovery based on heterogeneous information

  Gaëlle LELANDAIS

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• Transcriptional reprogramming in cancer cells triggered by glucose or glutamine starvation

  Nianli Sang

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• Comparison of transcription profiles in lung tissues between PRRSV resistant and susceptible pigs

  Yunliang Jiang, Feng Xing, Chenglan Jiang and Yanping Li

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• Metabolomics of Glioblastoma: Discovery of differentially regulated metabolites encoding tumorigenicity and treatment resistance in cell culture models

  Krishnan Thirumoorthy, Nicolaus Gordon, Disha Patel, Masa Okamoto, Arnab Chakravarti and Kamalakannan Palanichamy

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• Using time-course metabolomics to characterize the early interchange of substrates and putative signals during the establishment of the Populus-Laccaria symbiosis

  Timothy J. Tschaplinski

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• Structural and functional characterization of microcin C resistance peptidase MccF from Bacillus anthracis

  A. Joachimiak, B. Nocek, A. Tikhonov, M. Gu1, K. S. Makarova, G. Vondenhoff, A. Van Aerschot and K. Severinov

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• Micro RNA expression profiles and lipids and non-lipids responses to statins treatment among patients with primary hypercholesterolemia and treated with Pitastatin and Atorvastatin in a paralleled randomized controlled t

  Kuo-Liong Chien

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• Stage evolution of lipidomics and gene expressions associated with metabolic syndrome in HBx transgenic tumorigenesis

  Ih-Jen Su

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• Oncogenomic investigation in the field of colon cancer carcinogenesis

  Peter Pocza

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• IDO1 (indoleamine 2,3-dioxygenase 1) has a role in the Psychiatric manifestations of Latent Toxoplasmosis?

  BaharakKhabazghazvini

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• Metabolite analysis of biological mixtures using adaptable-shape modeling of an online NMR spectral database

  Roger Chylla

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• NMR metabolomics and drug discovery

  Robert Powers

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• Comparison of targeted and untargeted Stable Isotope Resolved Metabolomics (SIRM)

  Jeffrey Macdonald

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• Systems biology approach to cancer metabolomics: Dynamic data analysis through phylogenetics

  Hakima Amri

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• Streptomyces strain improvement using interspecies DNA Microarray System

  Eung-Soo Kim

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• Metabolomics and transcriptomics analyses of Acetaminophen and Carbon Tetrachloride induced hepatotoxicity

  Laura K. Schnackenberg

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• SIRT1 in metabolism and metabolic diseases

  Xiaoling Li

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• NMR based metabolomics in clinical and epidemiology screening

  M.Spraul, H.Schäfer and B.Schütz

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• NMR based metabolomics in clinical and epidemiology screening

  M.Spraul, H.Schäfer and B.Schütz

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• 1H NMR metabolomics combined with gene expression analysis for the determination of major metabolic differences between cancer cell lines

  Miroslava Cuperlovic-Culf

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• Interaction of fatty acid with myoglobin

  Lifan Shih

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• Ultrasensitive allosteric regulation of glycolytic efflux

  Yifan Xu

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• Micro Array-based cytogenomics, gene expression and epigenomics in colorectal Carcinoma

  Muhammad G Kibriya, Farzana Jasmine and Habibul Ahsan

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• Brain metabolomics identifies different mild therapeutic hypothermia treatments in an Oxygen-Glucose deprivation rodent model of neonatal asphyxia

  Lawrence Litt

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• Metabolomic variation of Brassica rapa (var. raapstelen) and Raphanus sativus L. at different developmental stages

  Muhammad Jahangir Awan

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• The developmental neurotoxicity of lead in rat primary aggregating brain cell cultures using transcriptomics and metabolomics approaches

  Hogberg HT, van Vliet E, Nolan SJ, Zhao L, Kleensang A, Odwin-DaCosta S and Hartung T

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• Metabolomics for understanding adverse drug effects

  Fozia Noor

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• Diabesity : Diabetes from a Surgical perspective

  Haydar A Nasser and Mohamad Tarek Berjaoui

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• The Golm Metabolome Database between Metabolite Substructure Prediction and Reporting of Metabolomic Data Sets for the Scientific Community

  Joachim Kopka, Jan Hummel, Nadine Strehmel and Dirk Walter

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• “AminoIndex technology” : A plasma free amino acid (PFAA) profiles-based screening indices for various cancers

  Akira Imaizumi

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• Metabolite profiling and dynamic 13C metabolomics of methane assimilation pathways in methanotrophic bacteria

  Song Yang, Martin Sadilek, Janet Bickford, Marina G. Kalyuzhnaya and Mary E. Lidstrom

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• The GCMS-based metabolomic study in mice with colitis induced by Dextran Sulfate Sodium

  Masaru Yoshida

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• Identification of metabolites as predictive biomarkers for dementia

  Malahat Mousavi

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• Metabolic profiling by UHR-Q-TOF analysis of dansylated metabolite extracts to study yeast Arginine synthesis mutants

  Aiko Barsch, Sandy Yates, Gabriela Zurek, Manhong Wu, Bob St. Onge, Sundari Suresh, Ron Davis and Gary Peltz

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• From hyperphagic rodents to diabetic complications: Targeted metabolomics in preclinical and clinical diabetology

  A.C. Gruber, U. Lundin, A. Dzien and K. M. Weinberger

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• C60 derivatives as novel matrices for analysis of small molecules by MALDI-TOF MS

  Shao Xiang XIONG, Jian An LIU, Shu ZHANG, Jing Chao and WEI

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• Analysis of molecular mechanisms associated to the adaptation of NS0 myeloma cell line to protein-free medium

  de la Luz K.Rashida

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• Metabolomics fingerprinting in clinical study of mutiple sclerosis disease

  Agnieska Smolinska

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• Adaptation of organisnms by resonance of RNA transcription with the cellulor redox

  Viktor Stolc

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• Novel human-associated uncultured bacterial pathogens, environmental models, and what metagenomics data tell us

  Cleber Ouverney

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• Genomic and Proteomic evidences of BPA involvement in Breast Cancer

  Mihi Yang

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• Repertoire of variants recruited by the environmental cues that occur during asexual reproduction

  Alain Robichon

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• Network based analysis of genome wide association data provides novel candidate genes for lipoprotein traits

  Amitabh Sharma

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• New insights into the early steps of adipocyte generation unveiled by transcriptomics

  Miguel Monteiro

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• Profiling trait anxiety: Transcriptome analysis reveals Cathepsin B (Ctsb) as a novel candidate gene for emotionality in mice

  Ludwig Czibere

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• Collective fluctuations guiding global biological responses

  Masa Tsuchiya, Vincent Piras, Masaru Tomita and Kumar Selvarajoo

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• In vitro biotinylation and proteomics identification of endothelial cell surface proteins post radiation in pursuit of vascular targets

  Margaret Simonian, Marcus A Stoodley and Mark P Molloy

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• Effect of sea cucumber collagen diet on learning and memory in mice and molecular correlates

  Xiurong Su

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• “OMICS” analysis of cadmium-induced lung cell transformation

  Yanming Xu, Jen-Fu Chiu and Andy T. Y. Lau

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• Metabolomic approaches to delineating fatty acid biosynthesis in the apicomplexan parasite Toxoplasma gondii

  James Ian MacRae

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• Metabolomics-based investigation of the lipid-lowering mechanism of Schisandrin B in nonalcoholic steatohepatitis

  Hiu Yee Anna KWAN, Kim-Chung Lee, Chi-Leung Chan and Wang-Fun Fong

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• Glyconectin proteoglycans: The self assembling molecular velcro mediating self non self recognition and adhesion implicated in evolution of multicellularity

  Gradimir Misevic

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• MicroRNAco-regulation of TET2 associated genes

  Lawrence Wing Chi CHAN

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• Combinatorial gene expression correlates to Neuronal Arbor Diversity

  Badea

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• Use of molecular probes and mass spectrometry for tracing metabolites of specific lipids

  Naomichi Baba1 Hiroko Tominaga and Arnold N. Onyango

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• Metabolomics study of the effect of omega-3 and vegetables on patients with type 2 diabetes reveals the metabolic alteration in plasma- phospholipids and ceramides

  Moazzami AA, Müllner E, Brath H, Forster E and Wagner KH

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• Cytomimetic glycan microarray for profiling Glycan-Protein interactions

  Xue-Long Sun

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• New nanoarray technologies for single cell omic analysis: Why and how?

  Gerard BenAssayag

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• Further developments in systems biology: Virtual scanning

  Graham Wilfred Ewing

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• Metabolomics data integration in tomato plant-fruit systems biology

  Rolin Dominqiue

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• MetDisease - A disease-centric view of metabolic networks

  Alla Karnovsky

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• Classification of physiologic/pathologic phenotypes in cell signaling networks: A mathematical approach

  Guanyu Wang

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• The Bio-toolkit suite of bioinformatic tools

  Martin R. Schiller

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• Systems biology warehousing: A benchmark of frameworks for effective data integration

  Thomas Triplet

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• Assaying the multiple energy-producing pathways of mammalian cells using biolog’s PMM/OmniLog cell-based assay platform

  John Z. Pietrzyk

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• Modeling Biological Systems as nonequilibrium relaxation structures by means of the kinetic equation

  Vladimir Aristov

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• Detection of developmental stages from DNA microarray time series and robust modeling of gene expression evolution in Drosophila

  Rooman Marianne

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• Automated reconstruction of tissue specific human metabolic networks and its potential impact on personalized medicine

  Adil Mardinoglu, Rasmus Agren, Natapol Pornputtapong, Intawat Nookaew, Sergio Bordel Velasco and Jens Nielsen

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• Automated metabolic pathway reconstruction based on structural grammars

  Rajat K. De and Somnath Tagore

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• A new computational approach to analysis the variability and regulation processes in drug metabolic systems based on iterative combinations of metabolic profiles

  Nabil SEMMAR

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• Adventures in personal genomics and whole omics profiling

  Michael Snyder, Rui Chen, Hugo Lam, Jennifer Li-Pook-Than, George Mias, Lihua Jiang, KonradKarczewski, Rick Dewey, ManojHariharan, Sara Hillemenyer, RajiniHaraksingh, Maeve O�Huallachain, Lukas Habegger, Rong Chen, Michael J. Clark, Joel Dudley, Suganthi, Teri Klein, Russ Altman, Atul Butte, Euan As

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• The mevalonate pathway: An integrated view of apoptosis control to abrogate cancer cell growth

  Laurent CORCOS

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• The systems biology of aspen wood development

  Torgeir R Hvidste

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• Multi-scale data integration of biological complexity: Towards rational drug design and systems-based medicine

  Sergio E. Baranzini

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• Metabolomics as a platform for high-throughput biomarker discovery in cancer

  Aalim M. Weljie

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• Discovering novel mechanisms of breast cancer brain metastasis using high throughput mass spectrometry-based technology

  Emily Chen

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• Network biology of the gut microbial “signaling metabolome” and consequences for identification of drug targets

  Marc-Emmanuel Dumas

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• Genetically encoded molecular automation algorithm orchestrates transcriptional reprogramming, photosynthesis and seed yield efficiency in Arabidopsis

  Stanislaw Karpinski

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• Clostridium thermocellum ethanol stress responses and tolerance mechanisms

  Steven D. Brown

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• CcpA, a Pleiotropic Key Regulator in Butanol-producing Clostridium acetobutylicum

  Weihong Jiang, Cong Ren, Yang Gu and Sheng Yang

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• Improved methods for metabolic kinetic modeling and complex bio-system analysis

  Ru-Dong Li

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• Reconstruction of sugar utilization pathways and regulons in the Clostridium genus

  Chen Yang, Lei Zhang, Xiaoqun Nie and Dmitry A. Rodionov

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• Computational models to integrate transcriptomic and proteomic data for predict abundance of undetected proteins

  Weiwen Zhang

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• Optimality in cellular response: Microorganisms anticipate and prepare in advance to environmental changes

  Amir Mitchell

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• Proteomics and Genomics of microorganisms for sequestration of carbon dioxide for production of biodiesel

  InduShekhar Thakur and Randhir Kumar Bharti

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• Microbiota and metabolic profiles of children with cow’s milk protein allergy and celiac disease determined by an “omics” approach

  Maria De Angelis

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• How melanoma treatments alter signaling networks on human lymphocytes after immuno- and chemotherapy- exposure

  Begonya Comin-Anduix

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• Integration of epigenomic and genomic data elucidates pathways in head and neck squamous cell carcinoma

  Michael F Ochs

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• Discovery of selective small-molecule inhibitors of key Protein-Protein interactions in the Wnt/ß-Catenin signaling pathway by rational design

  Haitao (Mark) Ji

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• Systems biology approach to cell signaling lead to new drug targets for glaucoma

  Thomas J. Lukas

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• Tumstatin and matrix Metaloprorotenase-2 Interactions and its angioinhibitory actions In-vitro and In-vivo

  Sudhakar Akul Yakkanti

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• Stress responses of resistant and susceptible tomato plants to Tomato yellow leaf curl virus infection are different

  Rena Gorovits

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• Metabolomic and transcriptomic Profiling Studies to Support the Identification of Biomarkers and to Understand the MOA of DGAT1 Inhibition

  Yejun (Eugene) Tan, Stephen J Gold, Judith Gorski, Jinqi Liu, Eric Muise, John R Thompson, Zhu Shen, Guanghui Hu and Shirly Pinto

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• Systems biology of oncogene-modulated drug sensitivity-resistance transition in PI3K/ PTEN/AKT signaling network

  Alexey Goltsov, Dana Faratian, Simon P Langdon, David J Harrison and James Bown

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• Conserved features of cancer cells define their sensitivity to HAMLETinduced death; c-Myc and glycolysis

  Catharina Svanborg

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• Intelligent method for risk estimation in breast cancer disease

  Raed I. Hamed

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• COX-2 Inhibitor prevents esophageal adenocarcinoma in Barrett’s Esophagus

  Fadhil Alamran

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• Resistance protein network obtained through genomic data integration

  Liliana López-Kleine and Alvaro L. Pérez

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• Oxidative stress in exercise: Possible new target for therapeutic intervention

  Vladimir Jakovljevic

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• TLR-4 and non alcoholic fatty liver disease (NAFLD): It is time to target?

  Ahmed Abu Shanab

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• PAK1 kinase promotes cell motility through CRK Serine phosphorylation in non-small cell lung cancer cells

  Fred Mortazavi

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• MAP Kinase modules: The power of two

  Angus Harding

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• Promotion of lipid raft mediated learning and memory pathways in mice fed with Acaudina leucoprocta hydrolyzate

  Yanyan Li, Jun Zhou, Chundan Zhang, Ye Li and Xiurong Su

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• Antilipolytic effect of proinsulin C-peptide in diabetic rat

  Ahmad Ghorbani, Gholam Hossein Ranjbar Omrani, Mousa Al-Reza Hadjzadeh and Masoumeh Varedi

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• Improved detection via nano Microfluidics-Based devices and nanodelivery to colon cancer therapy

  Jagat Kanwar

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• Conceptual questions in prophylactic oncology, creation of a preventive anticancerogenic vaccine

  Levon Mkrtchyan

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• Role of the CM2 protein in Influenza C virus replication

  Yasushi Muraki

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• Novel tool for monitoring nitrite and/ornitric oxide continuously in real time for drug discovery applications

  James H. Silver

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• Metabolomics in vivo: A tool to detect systemic toxicity in preclinical/ toxicological studies

  Kamp Hennicke

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• Anatomical dissection of metabolic systems of cancer by in vivo high-resolution imaging mass spectrometry

  Makoto Suematsu, Mitsuyo Ohmura, Akiko Kubo, Tsuyoshi Nakanishi and Yuki Sugiura

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• Standardization and metabonomics studies of hydro-ethanolic extract of Piper betel root in nanoparticles

  Plaban Bhattacharya

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• Development and validation of bioanalytical method for the quantitative estimation of Duloxetine in human plasma using ICMS/MS

  S. P. Pattanayak, A. Kaur, P. Anandan and P. Sunita

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• A novel metabolic feedback loop triggered by pyruvate kinase controls redox metabolism in respiring cells

  Markus Ralser

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• 5-lipoxigenase inhibitor and thyroid hormone analog attenuate global myocardial ischemia reperfusion injury after heterotopic heart transplantation in male rats

  Najah R. Hadi, Fadhil G. Yousif Al-Amran and Heider SH. Al-qussam

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