DOI: 10.37421/2157-7099.2023.14.682
Febrile neutropenia is a frequent complication in cancer patients and affects nearly 80% with hematological malignancies and 10%-50% with solid malignancies occurring most frequently during the first chemotherapy cycle. Bacterial Bloodstream Infections (BSIs) accounts for 10% to 25% of all febrile episodes and is considered the most common among the infectious complications in febrile neutropenic patients due to the lack of adequate inflammatory response and makes sepsis a significant cause of mortality in this particular setting.
Howard Zarate*
Cytology and histology are two foundational branches of biology and medicine that play crucial roles in understanding the structure and function of organisms. Both disciplines focus on studying the cellular composition of tissues, but they differ in their approach, methods, and the level of detail they provide. Cytology is concerned with the study of individual cells, whereas histology focuses on the study of tissues and organs, which are composed of many cells working together. Though related, the distinction between these two fields is important for various scientific and medical applications, including diagnosis, research, and treatment development.
Akinyelu Ngugi*
Pathologists are indispensable members of the healthcare team, playing a critical role in the diagnosis and treatment of diseases. While patients often interact primarily with general practitioners, specialists, or surgeons, it is the pathologist’s expertise that provides the cornerstone for accurate diagnosis and personalized care. Pathology, the branch of medicine that focuses on the study of diseases, involves examining tissues, cells, and body fluids to understand the causes, nature, and effects of diseases. Pathologists do this through a variety of diagnostic methods, including gross examination, microscopy, molecular techniques, and advanced imaging, which provide insights that guide clinical decision-making. Their contributions extend beyond mere identification of diseases; they help determine the severity, stage, and likely progression of conditions, directly influencing the treatment choices and outcomes for patients.
Popp Baumler*
Pathologists are indispensable members of the healthcare team, playing a critical role in the diagnosis and treatment of diseases. While patients often interact primarily with general practitioners, specialists, or surgeons, it is the pathologist’s expertise that provides the cornerstone for accurate diagnosis and personalized care. Pathology, the branch of medicine that focuses on the study of diseases, involves examining tissues, cells, and body fluids to understand the causes, nature, and effects of diseases. Pathologists do this through a variety of diagnostic methods, including gross examination, microscopy, molecular techniques, and advanced imaging, which provide insights that guide clinical decision-making. Their contributions extend beyond mere identification of diseases; they help determine the severity, stage, and likely progression of conditions, directly influencing the treatment choices and outcomes for patients.
Thu Long*
Clinical pathology is an integral part of modern medicine, focusing on diagnosing and managing diseases through laboratory testing. Traditionally, clinical pathology encompasses a broad range of tests, including blood, urine, and tissue examinations, to evaluate the underlying causes of a patient’s symptoms. However, the field has evolved rapidly over the past few decades, and one of the most exciting developments is the rise of precision diagnostics. Precision diagnostics is a revolutionary approach that aims to tailor medical care to the individual characteristics of each patient, including genetic, molecular, and environmental factors. This shift from generalized to personalized medicine has far-reaching implications for clinical pathology and the future of healthcare.
Titova Sosin*
The role of molecular pathology in precision medicine has emerged as a cornerstone in the evolution of modern healthcare. Over the past few decades, the intersection of molecular biology and pathology has paved the way for more targeted, individualized approaches to medical treatment, making significant strides toward enhancing diagnostic accuracy, treatment efficacy, and patient outcomes. Precision medicine, which is centered around tailoring medical treatments based on the genetic, molecular, and environmental characteristics of individual patients, has significantly benefited from the integration of molecular pathology. This approach goes beyond the traditional “one-size-fits-all” methodology and aims to provide therapies that are better suited to each patient’s unique biological makeup.
Loh Ma*
Histopathology is a specialized branch of pathology that plays a vital role in understanding disease mechanisms by examining tissue samples under a microscope. This discipline forms the foundation of medical diagnosis, offering insights into the cellular and structural abnormalities that characterize various diseases, including cancers, infections, and degenerative conditions. Through the detailed analysis of tissue architecture, cellular structures, and alterations induced by disease, histopathologists provide invaluable information that aids in diagnosing, staging, and monitoring disease progression. The significance of histopathology cannot be overstated as it helps in bridging the gap between clinical presentations and the microscopic features that define pathological conditions.
Nicolae Paulli*
Hematopathology, the study of blood diseases through microscopic examination, plays a pivotal role in diagnosing and understanding various hematological disorders, including leukemia’s, lymphomas, and myeloproliferative diseases. Traditionally, hematopathologists relied heavily on morphological features observed in blood smears, bone marrow aspirates, and lymph node biopsies, combined with clinical features and histopathological findings. However, as the complexity of hematological diseases has increased and our understanding of their molecular underpinnings has evolved, traditional diagnostic methods are no longer sufficient. The advent of molecular techniques has revolutionized hematopathology, offering more precise, accurate, and sensitive diagnostic tools that provide insight into the genetic and molecular mechanisms of these diseases.
Zuo Zhang*
Cytology, the study of cells, has long been a cornerstone of medical diagnostics. It involves examining cells from various body tissues to detect abnormalities that may signal disease, particularly cancer. Historically, cytological examination has been performed manually by trained professionals who analyze microscopic slides to identify irregularities in cell morphology. However, as technology advances, cytology is undergoing a transformative shift. The integration of digital imaging and Artificial Intelligence (AI) into cytological practices is poised to revolutionize the field, offering new opportunities for improved accuracy, efficiency, and accessibility in diagnosis. Digital imaging technologies have significantly enhanced the way cytologists capture and analyze cell samples.
Journal of Cytology & Histology received 2476 citations as per Google Scholar report
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