Neurological Disorders

Bobby Thomas

Bobby Thomas, PhD
Associate Professor, Departments of Pharmacology & Toxicology and Neurology
Georgia Health Science University, USA

Biography

Dr. Bobby Thomas is an Associate Professor of the Department of Pharmacology & Toxicology and Neurology in Georgia Health Science University. He completed his Ph.D. from Indian Institute of Chemical Biology, Jadavpur University, Kolkata in 2002. Dr. Bobby Thomas major interest is to study molecular mechanisms of neurodegeneration induced by genetic mutations, environmental toxicants and gene-environment interactions in Parkinson’s disease with a primary focus on mitochondrial dysfunction and stress signaling pathways involving oxidative stress and neuroinflammation.

Research Interest

Dr. Bobby Thomas main research is to study molecular mechanisms of neurodegeneration induced by genetic mutations, environmental toxicants and gene-environment interactions in Parkinson’s disease with a primary focus on mitochondrial dysfunction and stress signaling pathways involving oxidative stress and neuroinflammation. The ultimate goal is to utilize this mechanistic knowledge to develop tangible neuroprotective therapies for Parkinson's disease and perhaps other neurodegenerative disorders. Experimental approach is to use both genetic and toxicant induced cell culture and mouse models of Parkinson's disease, patient derived iPS cells and postmortem tissues. Major techniques that are routinely used in our lab include stereotactic surgery, HPLC, stereological cell counting, confocal imaging, immunohistochemistry and other standard molecular biology methods such as immunoblotting, RT-PCR, gene cloning, lentiviral and adeno-associated virus mediated gene transfer, magnetic cell sorting and flow cytometry.