Molecular Biology: Open Access

Lei Tian

Lei Tian
University of Kentucky
USA

Biography

1996 – 2001 Bachelor of Medicine /MD, Tongji Medical College, Huazhong University of Science and Technology, China

2002 – 2005 Master of Medicine, Tongji Medical College, Huazhong University of Science and Technology, China; Major: Hematology/Internal Medicine;

2006 – 2011 Ph.D., University of Kentucky, USA., Major: Toxicology.

Research Interest

My research has focused on the mechanism of genome stability maintenance, especially the molecular biology mechanism of DNA repair such as mismatch repair and hairpin repair, and also disease related to genome instability. I am best known for my research on characterization of mismatch recognition and for defining BRCA1 as a new Fanconi anemia gene. Currently, I'm also working on the mechanism of ubiquitinating and deubuquitinating regulation of DNA repair and inflammation signaling.