Cancer Science & Therapy

Vincent L Wilson

Biography

Vincent Wilson is Professor of Toxicology in the Department of Environmental Sciences, School of the Coast & Environment at Louisiana State University, Baton Rouge, Louisiana. He received his PhD in Pharmacology & Toxicology from Oregon State University in 1980 and proceeded to postdoctoral studies in molecular genetics under the direction of Dr. Peter A. Jones at the University of Southern California Comprehensive Cancer Center.  With a focus on chemical carcinogenesis, Vincent then spent five years at the National Cancer Institute, NIH, Bethesda, MD, in the Laboratory for Human Carcinogenesis, under the direction of Dr. Curt Harris.  The attraction of an offer to build, develop and run a laboratory for DNA diagnostics for clinical genetics and oncology services drew him out of NCI to The Children’s Hospital, Denver, CO, and the Department of Pathology, University of Colorado Health Sciences Center for six years before accepting a faculty position at the Louisiana State University in 1994.  He served as Chair, Interdepartmental Program in Toxicology at LSU for eleven years.

Research Interest

1) Mechanisms in mutagenesis and carcinogenesis; 2) Determination of the importance of changes in DNA 5-methyldeoxycytidine and chromatin modification patterns to the physiologic and perturbed processes of embryogenesis, differentiation, aging, carcinogenesis, and epigenetic instability; 3) Genetic processes involved in aging, mutagenesis and carcinogenesis; 4) Single base instability, hypermutable phenotypes and oncogenic mutation frequencies; 5) Genotoxic markers of diagnostic value for environmental and human biomonitoring; 6) Genetic markers of diagnostic and prognostic value.