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Articles On Congenital Nevi | Open Access Journals
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Journal of Tissue Science and Engineering

ISSN: 2157-7552

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Articles On Congenital Nevi

Melanocytic nevus are benign overgrowth of melanocytic cells (also called nevus cells) arranged in nests in the epidermis, dermis, or other tissues.1,2

The melanocytic nevus present at birth is, by consensus, defined as congenital. Some authors, however, also include in this definition melanocytic nevus which develops up to the age of six months, in the first year or even up to two years.1-5 Although the congenital melanocytic blot( CMN) develops all along intrauterine life, the occurrence of these late congenital nevuses could be explained by the insufficient initial production of melanin and / or by the small size of the nevus at the beginning, which hinders its detection. 9

The giant congenital melanocytic nevus (GCMN) is generally defined as a congenital melanocytic lesion that will reach at least 20 cm in adult life.

Despite its rarity, GCMN is important for its association with serious complications such as malignant melanoma and involvement of the central nervous system (CNS), as well as a major psychosocial impact on the patient and his family, due to his unsightly appearance.6,11,21,22 The question of deciding which is the best therapeutic approach in these cases also causes distress for the medical team, due to the controversies surrounding the cure of these lesions - which arises largely from uncertainties about the risks of complications.13,23

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