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Articles On Psoriasis | Open Access Journals
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Journal of Dermatology and Dermatologic Diseases

ISSN: 2684-4281

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Articles On Psoriasis

Research on the pathogenesis of psoriasis has greatly increased knowledge about the biology of the skin in general. In the past 15 years, advances in understanding the pathogenesis of psoriasis have resulted in highly effective, targeted therapies that provide critical insight into the pathogenesis of chronic inflammatory diseases with a dominant axis IL-23 / Th17. This review discusses the mechanisms involved in the onset and development of the disease, as well as the therapeutic options that have emerged from dissection of the inflammatory psoriatic pathways. Our discussion begins by addressing the inflammatory pathways and key cell types that initiate and perpetuate psoriatic inflammation. Next, we describe the role of genetics, associated epigenetic mechanisms, and the interaction of skin flora in the pathophysiology of psoriasis. Finally, we include a comprehensive review of well-established and widely available therapies and new targeted medications.

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Journal of Dermatology and Dermatologic Diseases received 4 citations as per Google Scholar report

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