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Bone Marrow Seminars | Open Access Journals
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Journal of Spine

ISSN: 2165-7939

Open Access

Bone Marrow Seminars

 

Preterm deliveries account for 10% of live births in the US. USA And the survival of premature babies has improved over the years with advances in perinatal and neonatal care. Almost 25-30% of preterm infants with a birth weight less than 1250 grams develop bronchopulmonary dysplasia (DBP) characterized by abnormal alveolar and vascular development during a critical stage of postnatal lung development. Animal models of DBP suggest that abnormal pulmonary microvascular development leads to failure of alveolar development, and strategies that promote vascular development result in better lung alveolarization. Additionally, low levels of circulating endothelial progenitors and bone marrow derivatives have been observed in the blood of neonatal mice exposed to hyperoxia that develop DBP, suggesting that endothelial progenitors derived from bone marrow may play a role in lung development. neonatal. A human study reported lower levels of endothelial colony forming cells (ECFCs) in umbilical cord blood from premature infants who developed BPD than in umbilical cord blood from premature infants who did not develop BPD. However, others have observed higher or equivalent numbers of ECFC counts in umbilical cord blood from preterm deliveries compared to umbilical cord blood at term. Hisham Abdel-Azim, circulating endothelial progenitors and bone marrow derived cells as biomarkers for the risk of bronchopulmonary dysplasia

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Relevant Topics in Neuroscience & Psychology

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Citations: 2022

Journal of Spine received 2022 citations as per Google Scholar report

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