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Cell Fate Journals | Open Access Journals
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Journal of Immunobiology

ISSN: 2476-1966

Open Access

Cell Fate Journals

In developmental biology, the main perspective is to understand how a cell develops in an organism means how cell fate is determined. Neural stem/progenitor cells can be a powerful tool for neuronal repair of the damaged brain. Many of the current challenges of stem cell therapies revolve around the problem that stem cells do not survive, migrate, proliferate and differentiate as much as we hoped. The interaction between neural progenitor cells and the immune system is essential for the effective use of stem cell transplantation. Cytokines play an important role in determining the inflammatory microenvironment and have also been shown to have effects on the differentiation, proliferation, migration and survival of neural progenitor cells. The effects of cytokines on the fate of neural stem cells are more complex; the distinction between anti-inflammatory and pro-inflammatory cytokines is not simple and varies depending on conditions such as the concentration of cytokines and the area of ​​transplantation. Transplantation of neural progenitor cells itself causes an inflammatory response, which in turn influences the fate of neural progenitor cells and the success or failure of a transplant. The niche in which neural progenitor cells reside determines the fate of neural progenitor cells, and this niche is partially controlled by the components of the immune system.

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Conference Proceedings

Relevant Topics in Immunology & Microbiology

Google Scholar citation report
Citations: 34

Journal of Immunobiology received 34 citations as per Google Scholar report

Journal of Immunobiology peer review process verified at publons

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