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Human Epidermal Growth Factor Receptor | Open Access Journals
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Journal of Clinical Neurology and Neurosurgery

ISSN: 2684-6012

Open Access

Human Epidermal Growth Factor Receptor

The epidermal growth factor receptor is a protein of transmembrane of extracellular protein ligands that act as receptor for agents of the epidermal growth factor family (EGF family). The receptor of epidermal growth factor is a member of the ErbB family, a subfamily of closely related four tyrosine kinases receptor: EGFR (ErbB-1), HER2/neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). In most of the cancer types, EGFR expression or activity is affected by mutations which results in cancer. EGFR deficient signaling and other receptors such as tyrosine kinases in humans is associated with disorders or diseases such as Alzheimer's, while its expression is linked with the development of a different kinds of tumors.   

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