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Insulin Resistance | Open Access Journals
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Journal of Diabetic Complications & Medicine

ISSN: 2475-3211

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Insulin Resistance

Insulin may be a hormone made by the pancreas that helps glucose in your blood enter cells in your muscle, fat, and liver, where it’s used for energy. Glucose comes from the food you eat. The liver also makes glucose in times of need, like when you’re fasting. When blood sugar, also called blood glucose, levels rise after you eat, your pancreas releases insulin into the blood. Insulin then lowers blood sugar to stay within the normal range.

People who have genetic or lifestyle risk factors are more likely to develop insulin resistance or prediabetes. Risk factors include

overweight or obesity

age 45 or older

a parent, brother, or sister with diabetes

African American, Alaska Native, American Indian, Asian American, Hispanic/Latino, Native Hawaiian, or Pacific Islander American ethnicity

physical inactivity

health conditions like high vital sign and abnormal cholesterol levels

a history of gestational diabetes

a history of heart disease or stroke

polycystic ovary syndrome also called PCOS

People who have metabolic syndrome—a combination of high vital sign, abnormal cholesterol levels, and enormous waist size—are more likely to possess prediabetes.

Along with these risk factors, other things which will contribute to insulin resistance include

certain medicines, such as glucocorticoids NIH external link, some antipsychotics NIH external link, and some medicines for HIV NIH external link

hormonal disorders, such as Cushing’s syndrome and acromegaly

sleep problems, especially sleep apnea NIH external link

Although you can’t change risk factors like case history, age, or ethnicity, you'll change lifestyle risk factors around eating, physical activity, and weight. These lifestyle changes can lower your chances of developing insulin resistance or prediabetes.

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Citations: 102

Journal of Diabetic Complications & Medicine received 102 citations as per Google Scholar report

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