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Molecular Diagnostics | Open Access Journals
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Molecular Biomarkers & Diagnosis

ISSN: 2155-9929

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Molecular Diagnostics

Molecular diagnostics is a set of techniques used in the genome to examine biological markers and protect the genetic code of the organism and how their cells express their genes as proteins through the application of molecular biology to medical research. The technique is used for diagnosing and tracking illness, identifying risk and determining which treatments function best for individual patients. These tests are useful in a range of medical specialties, including infectious disease, oncology, typing of human leucocyte antigens (which investigates and predicts immune function), coagulation, and pharmacogenomics — the genetic prediction of which drugs will work best. Many of the single nucleotide polymorphisms of a patient — slight variations in their DNA can help determine how quickly they are going to metabolize different drugs; this is called pharmacogenomics. For example, the CYP2C19 enzyme metabolizes many drugs into their active forms, such as the anti-coagulant agent Clopidogrel. Infectious diseases such as chlamydia, influenza virus, and tuberculosis are identified with molecular diagnostics; or specific strains such as H1N1 virus. Genetic identification can be swift; for example, the malaria parasite is diagnosed by a loop-mediated isothermal amplification test and is rough enough for developing countries.

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Citations: 2054

Molecular Biomarkers & Diagnosis received 2054 citations as per Google Scholar report

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