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Molecular Biomarkers & Diagnosis

ISSN: 2155-9929

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NMR

Nuclear magnetic resonance ( NMR) is a physical observation method in which nuclei in a solid, constant magnetic field are disrupted by a weak oscillating magnetic field and react by generating an electromagnetic signal with a magnetic field frequency characteristic at the nucleus. This cycle takes place near resonance, when the oscillation frequency matches the nuclei 's intrinsic frequency, which depends on the strength of the static magnetic field, the chemical environment and the isotope's magnetic properties involved; in practical applications with static magnetic fields up to approx. The frequency of 20 tesla is similar to VHF and UHF TV broadcasts. Nuclear magnetic resonance spectroscopy is commonly used to determine the structure of organic molecules in solution, as well as to study molecular physics, crystals and non-cristalline materials. NMR is also routinely used in advanced techniques for medical imaging, such as magnetic resonance imaging ( MRI).

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