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Remyelination | Open Access Journals
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Mental Disorders and Treatment

ISSN: 2471-271X

Open Access

Remyelination

Remyelination is the process by which precursor cells of oligodendrocytes are propagated to form oligodendrocytes to create new myelin sheaths on demyelinated axons in CNS. It is a mechanism that is controlled naturally within the body and appears to be very successful in a stable CNS. The process produces a thinner sheath of myelin than normal, but it helps protect the axon from further injury, from overall degeneration, and once again proves to increase conductance. The underlying remyelination mechanisms are being studied in the hope of discovering therapies for Demyelinating disorders, such as multiple sclerosis. Remyelination is triggered and controlled by a variety of factors that control the migration and differentiation of Oligodendrocyte Precursor Cells around the lesion sites. Remyelination in the structure of the developed myelin appears different from developmental myelination. Reasons for this are uncertain but the axon 's proper role is restored regardless of.

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