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Telomerase | Open Access Journals
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Molecular and Genetic Medicine

ISSN: 1747-0862

Open Access

Telomerase

Research from the laboratory of Professor Julian Chen in the School of Molecular Sciences at Arizona State University recently uncovered a crucial step in the telomerase enzyme catalytic cycle. This catalytic cycle determines the ability of the human telomerase enzyme to synthesize DNA "repeats" (specific DNA segments of six nucleotides) onto chromosome ends, and so afford immortality in cells. Understanding the underlying mechanism of telomerase action offers new avenues toward effective anti-aging therapeutics. illustration depicting the enzyme telomerase This figure depicts the enzyme telomerase as well as telomeres relative to a chromosome.

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Relevant Topics in Genetics & Molecular Biology

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Citations: 3919

Molecular and Genetic Medicine received 3919 citations as per Google Scholar report

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