GET THE APP

Fluorescence Morphometry was Used to Quantify the Changes in Drug Response Caused by Simulated Microgravity in Cancer Cells
..

Journal of Cytology & Histology

ISSN: 2157-7099

Open Access

Perspective - (2023) Volume 14, Issue 4

Fluorescence Morphometry was Used to Quantify the Changes in Drug Response Caused by Simulated Microgravity in Cancer Cells

Spincher Kinley*
*Correspondence: Spincher Kinley, Department of Biology, Creighton University, Omaha, NE 68178, USA, Email:
Department of Biology, Creighton University, Omaha, NE 68178, USA

Received: 01-Jul-2023, Manuscript No. jch-23-111095; Editor assigned: 03-Jul-2023, Pre QC No. P-111095; Reviewed: 15-Jul-2023, QC No. Q-111095; Revised: 20-Jul-2023, Manuscript No. R-111095; Published: 27-Jul-2023 , DOI: 10.37421/2157-7099.2023.14.699
Citation: Kinley, Spincher. “Fluorescence Morphometry was Used to Quantify the Changes in Drug Response Caused by Simulated Microgravity in Cancer Cells." J Cytol Histol 14 (2023): 699.
Copyright: © 2023 Kinley S. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Introduction

Cell division is a fundamental biological process that underlies the growth, development, and maintenance of all living organisms. It is a precisely regulated mechanism that ensures the accurate distribution of genetic material and other cellular components between daughter cells. This intricate process plays a pivotal role in various biological functions, including embryogenesis, tissue repair, and the propagation of genetic information. In this comprehensive exploration, we delve into the mechanisms, types, and significance of cell division, shedding light on the intricate dance of fluorescence morphometry life at the cellular level.

Description

Cell division occurs through two primary mechanisms of morphometry. While both processes involve the division of a single cell into two or more daughter cells, they serve distinct purposes and take place in different contexts. Mitosis is the most common form of cell division and is responsible for the growth, development, and maintenance of multicellular organisms. During mitosis, a single eukaryotic cell undergoes a series of highly orchestrated steps to produce two genetically identical daughter cells. This process can be divided into several distinct phases: prophase, metaphase, anaphase, and telophase [1]. The chromatin in the cell's nucleus condenses into visible chromosomes, each consisting of two sister chromatids joined at the centromere. The nuclear envelope begins to break down, and the mitotic spindle apparatus, composed of microtubules, starts to form. The condensed chromosomes align along the equatorial plane of the cell, known as the metaphase plate drug. This precise alignment ensures that each daughter cell will receive the same complement of genetic material [2].

The centromeres split, separating the sister chromatids. Microtubules of the mitotic spindle contract, pulling the chromatids to opposite poles of the cell. This guarantees that each daughter cell receives an identical set of chromosomes. The separated chromatids reach the poles of the cell, and the nuclear envelope begins to re-form around each set of chromosomes. This marks the completion of nuclear division [3]. Following telophase, the cell undergoes cytokinesis, the division of the cytoplasm and other organelles between the daughter cells. In animal cells, a contractile ring of actin filaments forms at the cell's equator, pinching the cell in two. In plant cells, a new cell wall, known as the cell plate, is synthesized between the daughter nuclei [3].

Mitosis plays a critical role in growth, development, and tissue repair. It ensures that each new cell produced maintains the same genetic information as the parent cell, thereby maintaining genetic stability within an organism. While mitosis results in genetically identical daughter cells, meiosis is a specialized form of cell division that leads to the formation of gametes (sperm and egg cells) with half the normal chromosome number. This reduction in chromosome number is essential for sexual reproduction and the generation of genetic diversity within a population [4,5].

The study of cell division continues to be a dynamic field of research, with ongoing discoveries revealing new insights into the intricacies of this fundamental process. Advancements in molecular biology, microscopy, and imaging techniques have enabled scientists to uncover the molecular mechanisms that govern cell division, shedding light on the complex interactions between proteins, nucleic acids, and organelles. As our understanding of cell division deepens, its implications for health, disease, and evolution become increasingly apparent. Targeted therapies for cancer, strategies to enhance tissue regeneration, and approaches to prevent genetic disorders are all areas that stand to benefit from a comprehensive understanding of cell division.

Conclusion

In conclusion, cell division is a captivating dance of life that underlies the growth, development, and adaptation of all living organisms. From the precise orchestration of mitosis to the intricate dance of meiosis, cell division shapes the biological landscape, ensuring genetic stability and diversity while contributing to the myriad wonders of life on Earth. As technology and knowledge continue to advance, the study of cell division will undoubtedly yield even greater insights, illuminating the mysteries of existence at the cellular level.

References

  1. Hodkinson, P. D., R. A. Anderton, B. N. Posselt and K. J. Fong. "An overview of space medicine." Br J Anaesth 119 (2017): i143-i153.
  2. Google Scholar, Crossref, Indexed at

  3. Roberts, Donna R., Moritz H. Albrecht, Heather R. Collins and Davud Asemani, et al. "Effects of spaceflight on astronaut brain structure as indicated on MRI." N Engl J Med 377 (2017): 1746-1753.
  4. Google Scholar, Crossref, Indexed at

  5. Blue, Rebecca S., Tina M. Bayuse, Vernie R. Daniels and Virginia E. Wotring, et al. "Supplying a pharmacy for NASA exploration spaceflight: Challenges and current understanding." NPJ Microgravity 5 (2019): 14.
  6. Google Scholar, Crossref, Indexed at

  7. Prasanth, Devika, Sindhuja Suresh, Sruti Prathivadhi-Bhayankaram and Michael Mimlitz, et al. "Microgravity modulates effects of chemotherapeutic drugs on cancer cell migration." Life 10 (2020): 162.
  8. Google Scholar, Crossref, Indexed at

  9. Hanahan, Douglas and Robert A. Weinberg. "Hallmarks of cancer: The next generation." Cell 144 (2011): 646-674.
  10. Google Scholar, Crossref, Indexed at

Google Scholar citation report
Citations: 2476

Journal of Cytology & Histology received 2476 citations as per Google Scholar report

Journal of Cytology & Histology peer review process verified at publons

Indexed In

 
arrow_upward arrow_upward