Histopathology in Veterinary Medicine: Advancements and Applications

Verena Habermaass^*
*Correspondence: Verena Habermaass, Department of Veterinary Sciences, University of Pisa, Via Livornese Lato Monte, Italy, Email:

Introduction

Histopathology is a fundamental discipline in veterinary medicine that has undergone remarkable advancements in recent years. This article explores the evolving landscape of histopathology in veterinary medicine, focusing on the latest technologies, applications, and their impact on animal healthcare. We also discuss the importance of histopathology in disease diagnosis and treatment, highlighting the crucial role it plays in improving the overall well-being of animals. Histopathology is a cornerstone of veterinary medicine, serving as an indispensable tool for diagnosing and understanding diseases in animals. Over the years, the field of veterinary histopathology has witnessed substantial advancements, thanks to innovations in technology and methodology. These advancements have broadened the applications of histopathology in veterinary medicine, revolutionizing disease diagnosis and treatment for animals [1].

Description

Immunohistochemistry has become a valuable technique in veterinary histopathology. It allows pathologists to detect specific antigens within tissues by using labeled antibodies. IHC has found applications in diagnosing infectious diseases, identifying tumor markers, and understanding immune responses in animals. The integration of molecular biology techniques with histopathology has given rise to molecular histopathology. It enables the examination of genetic and epigenetic changes within tissues. Molecular histopathology is particularly important in understanding the genetic basis of hereditary diseases in animals. Digital pathology involves the scanning and digitization of histological slides, allowing for remote viewing, storage, and analysis. This technology has improved collaboration among veterinary pathologists and enabled the creation of extensive digital slide archives for research and education. Multiplex immunohistochemistry and in situ hybridization techniques enable the simultaneous detection of multiple antigens or genes within the same tissue section. This advancement is especially useful in characterizing complex diseases in animals, such as cancer. Histopathology is crucial in diagnosing and staging various types of cancer in animals. Pathologists examine tissue samples to determine the type, grade, and extent of tumors, helping veterinarians make informed decisions regarding treatment options [2].

Histopathology plays a vital role in identifying the causative agents of infectious diseases in animals. Through the examination of tissues, pathologists can detect and characterize parasites, bacteria, viruses, and fungi, aiding in the development of treatment and prevention strategies. Veterinary histopathology is instrumental in understanding hereditary diseases that affect animals. Molecular histopathologies techniques help uncover genetic mutations responsible for inherited conditions, allowing for selective breeding and genetic counseling. Histopathology is used in pharmacological and toxicological studies to evaluate the effects of drugs and toxins on animal tissues. This information is crucial for drug development and safety assessments. In cases of animal abuse, poisoning, or unexplained deaths, forensic veterinary pathologists use histopathology to determine the cause of death and gather evidence for legal proceedings [3].

Early diagnosis of diseases is critical for successful treatment. Histopathology enables veterinarians to identify diseases at a microscopic level, often before clinical symptoms manifest. This early detection can lead to more effective treatment options and improved outcomes for animals. Understanding the histopathological characteristics of a disease helps veterinarians tailor treatment plans to the specific needs of each patient. This personalized approach can optimize the use of medication, surgery, and other therapeutic modalities. Histopathology has been instrumental in advancing cancer therapy for animals. By characterizing tumor types and their genetic profiles, veterinarians can select targeted treatments, such as chemotherapy, immunotherapy, and radiation therapy. In cases of infectious diseases, histopathology is essential for identifying the causative agents and understanding their pathology. This knowledge is critical for implementing effective control measures and preventing disease spread. With the help of histopathology and molecular techniques, breeders can make informed decisions to reduce the incidence of hereditary diseases in animal populations. This has a long-term impact on the health of specific breeds [4,5].

Conclusion

Histopathology in veterinary medicine has made significant strides, thanks to advancements in technology and methodology. These innovations have expanded the scope of histopathological applications, making it an invaluable tool for disease diagnosis and treatment in animals. From cancer diagnosis to infectious disease control and hereditary disease management, histopathology plays a pivotal role in improving animal healthcare. As the field continues to evolve, it is expected to further enhance our ability to understand and care for the health of our animal companions. In the future, histopathology in veterinary medicine is likely to see further developments. This may include the integration of artificial intelligence for automated analysis, improved point-of-care diagnostics, and the expansion of digital pathology applications. Additionally, efforts to make advanced histopathology more accessible and affordable to a wider range of animal owners and caregivers will continue to be a focus in the field.

Acknowledgement

None.

Conflict of Interest

There are no conflicts of interest by author.

References

1. Holmes, Elaine, Jia V. Li, Julian R. Marchesi and Jeremy K. Nicholson. "Gut microbiota composition and activity in relation to host metabolic phenotype and disease risk." Cell Metab 16 (2012): 559-564.

Google Scholar, Crossref, Indexed at

2. Li, You, Ruqi Tang, Patrick SC Leung and M. Eric Gershwin, et al. "Bile acids and intestinal microbiota in autoimmune cholestatic liver diseases." Autoimmun Rev 16 (2017): 885-896.

Google Scholar, Crossref, Indexed at

3. Dhillon, Amandeep K., Martin Kummen, Marius Trøseid and Sissel Åkra, et al. "Circulating markers of gut barrier function associated with disease severity in primary sclerosing cholangitis." Liver Int 39 (2019): 371-381.

Google Scholar, Crossref, Indexed at

4. Betrapally, Naga S., Patrick M. Gillevet and Jasmohan S. Bajaj. "Gut microbiome and liver disease." Transl Res 179 (2017): 49-59.

Google Scholar, Crossref, Indexed at

5. Handl, Stefanie, Alexander J. German, Shelley L. Holden and Scot E. Dowd, et al. "Faecal microbiota in lean and obese dogs." FEMS Microbiol Ecol 84 (2013): 332-343.

Google Scholar, Crossref, Indexed at