Innovations in Radiation Therapy: Enhancing Cancer Treatment

Liam Spurr^*
*Correspondence: Liam Spurr, Department of Radiation and Cellular Oncology, University of Chicago, Chicago, IL, USA, Email:

Introduction

Radiation therapy, a cornerstone in the treatment of cancer for decades, has witnessed remarkable advancements in recent years. These innovations have transformed the landscape of cancer care, making treatment more precise, effective and patient-friendly. In this article, we will explore the exciting innovations in radiation therapy that are enhancing cancer treatment, offering new hope to patients worldwide.

One of the most significant breakthroughs in radiation therapy is Image- Guided Radiation Therapy (IGRT). IGRT combines real-time imaging technology, such as CT scans or MRI, with radiation therapy to precisely target tumors. By continuously monitoring the tumor's position, shape and size during treatment, IGRT ensures that radiation beams are accurately delivered, sparing healthy tissue and minimizing side effects. This level of precision allows for higher doses of radiation to be administered to the tumor, increasing the chances of eradicating cancer cells. Stereotactic Radiosurgery (SRS) and Stereotactic Body Radiation Therapy (SBRT) are cutting-edge techniques that deliver extremely high doses of radiation with pinpoint accuracy. SRS is used for treating brain tumors and lesions, while SBRT extends this approach to tumors elsewhere in the body, like the lungs and liver. These treatments are non-invasive, require fewer sessions than conventional radiation therapy and result in minimal damage to surrounding healthy tissue. Patients often experience shorter recovery times and reduced side effects [1].

Description

Proton therapy is an innovative form of radiation therapy that uses protons, rather than X-rays, to deliver radiation to tumors. Protons have unique properties that allow for precise targeting of cancer cells while sparing nearby healthy tissue. This is particularly valuable in treating pediatric cancers and tumors located near critical organs. Proton therapy is gradually becoming more accessible, with an increasing number of proton therapy centers worldwide. Magnetic Resonanceguided Linear Accelerator (MR-Linac) combines a radiation therapy machine with an MRI scanner. This integration allows oncologists to visualize tumors and surrounding structures in real-time during treatment, making adjustments as needed. MR-Linac provides a dynamic, adaptive approach to radiation therapy, ensuring that the radiation is precisely delivered to moving targets, like tumors affected by breathing or body movement [2].

Particle beam therapy, which includes carbon-ion and heavy-ion therapies, is an emerging field in radiation therapy. These therapies use charged particles to deliver radiation to tumors with high precision. They are particularly effective against certain types of cancer that are resistant to conventional radiation therapy. While not yet widely available, ongoing research and the construction of particle therapy centers show promise for the future of cancer treatment. Particle beam therapy, also known as particle therapy, is an advanced form of radiation therapy used in the treatment of cancer. Unlike traditional radiation therapy, which uses X-rays (photons) to target and destroy cancer cells, particle beam therapy uses charged particles, such as protons or heavy ions, to deliver radiation with greater precision and control. This innovative approach offers several advantages in cancer treatment. Particle beams have unique physical properties that allow them to deposit most of their energy directly into the tumor tissue while minimizing damage to surrounding healthy tissue. This precision is particularly beneficial when treating tumors located near critical structures or in pediatric patients, as it reduces the risk of long-term side effects [3].

Particle beams have a distinct advantage over conventional X-ray radiation in terms of reduced exit dose. They release their energy at a specific depth within the tissue, sparing normal tissues beyond that depth. This characteristic decreases the risk of radiation exposure to healthy organs and tissues. Particle beam therapy is particularly effective in treating radioresistant tumors those that do not respond well to conventional radiation therapy. Heavy ions, in particular, have been successful in targeting and eradicating such tumors. Children are more sensitive to the long-term effects of radiation. Particle beam therapy's ability to spare healthy tissue and minimize radiation exposure to developing organs makes it an ideal choice for pediatric cancer treatment. Patients undergoing particle beam therapy often experience fewer acute and chronic side effects compared to conventional radiation therapy [4].

This can lead to an improved quality of life during and after treatment. Proton therapy uses protons, positively charged particles, to deliver radiation. Protons have a unique characteristic called the Bragg peak, which allows them to deposit most of their energy precisely at the tumor site, sparing surrounding tissues. Proton therapy is widely available in many cancer centers. Heavy ion therapy, also known as hadron therapy, uses heavy ions such as carbon or helium nuclei to treat cancer. Heavy ions are particularly effective against radioresistant tumors. While not as widely available as proton therapy, heavy ion therapy has shown promise in clinical trials. Particle beam therapy represents a significant advancement in cancer treatment, offering enhanced precision and reduced side effects compared to conventional radiation therapy. As research and technology continue to evolve, particle beam therapy is likely to become an increasingly important tool in the fight against cancer, providing hope for improved outcomes and a higher quality of life for cancer patients [5].

Conclusion

Innovations in radiation therapy are revolutionizing the way we treat cancer. These advancements offer hope to patients by providing more effective, precise and patient-friendly treatment options. As research continues and technology evolves, the field of radiation therapy will likely see even more breakthroughs, ultimately improving cancer outcomes and enhancing the quality of life for those undergoing treatment. It is a testament to the relentless pursuit of medical progress in the fight against cancer, offering new rays of hope for patients and their families.

References

1. Lukanović, David, Maruša Herzog, Borut Kobal and Katarina Černe. "The contribution of copper efflux transporters ATP7A and ATP7B to chemoresistance and personalized medicine in ovarian cancer." Biomed Pharm 129 (2020): 110401.

Google Scholar, Crossref, Indexed at

2. Ferlay, Jacques, Isabelle Soerjomataram, Rajesh Dikshit and Sultan Eser, et al. "Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012." Int J Cancer 136 (2015): E359-E386.

Google Scholar, Crossref, Indexed at

3. Fridman, Gregory, Gary Friedman, Alexander Gutsol and Anatoly B. Shekhter, et al. "Applied plasma medicine." Plasma Process Polym 5 (2008): 503-533.

Google Scholar, Crossref

4. Lin, Li, Dayun Yan, Taeyoung Lee and Michael Keidar. "Self‐adaptive plasma chemistry and intelligent plasma medicine." Adv Intell Syst 4 (2022): 2100112.

Google Scholar, Crossref, Indexed at

5. Wenzel, Thomas, Daniel A. Carvajal Berrio, Christl Reisenauer and Shannon Layland, et al. "Trans-mucosal efficacy of non-thermal plasma treatment on cervical cancer tissue and human cervix uteri by a next generation electrosurgical argon plasma device." Cancers 12 (2020): 267.

Google Scholar, Crossref, Indexed at