Kidney Infection: Causes, Symptoms and Treatment

Petura Lopeea^*
*Correspondence: Petura Lopeea, Department of Nephrology, University of São Paulo, São Paulo, Brazil, Email:

Introduction

Kidney infections, also known as pyelonephritis, are a type of urinary tract infection that specifically affects one or both kidneys. While often treatable, kidney infections can lead to serious complications if left untreated. Understanding the causes, symptoms, and treatment options for kidney infections is essential for prompt diagnosis and effective management. The most common cause of kidney infection is bacteria, typically originating from a lower urinary tract infection that ascends to the kidneys. Escherichia coli (E. coli) is the bacterium most frequently responsible for kidney infections. Any obstruction in the urinary tract, such as kidney stones or an enlarged prostate gland, can impede the flow of urine and increase the risk of bacterial growth and infection. Individuals with weakened immune systems, such as those with diabetes, HIV/AIDS, or undergoing chemotherapy, are more susceptible to kidney infections. Women are more prone to kidney infections than men due to their shorter urethra, which allows bacteria easier access to the bladder and kidneys. Long-term use of urinary catheters increases the risk of urinary tract infections, including kidney infections, particularly in hospitalized patients or those with urinary retention issues [1].

Description

A high fever (often exceeding 101°F or 38.3°C) accompanied by chills is a common symptom of kidney infection, indicating the body's immune response to the infection. Pain in the back or side (flank pain), usually on one side of the body, is a hallmark symptom of kidney infection. The pain may be dull and achy or sharp and intense. Individuals with kidney infections often experience a strong and persistent urge to urinate, accompanied by pain or burning during urination. Urine may appear cloudy, have an unusual odor, or contain blood, pus, or sediment due to the presence of bacteria and inflammation in the urinary tract. Some individuals with kidney infections may experience nausea, vomiting, or loss of appetite, often accompanied by abdominal discomfort. The primary treatment for kidney infections involves antibiotics to eradicate the underlying bacterial infection. The choice of antibiotic and duration of treatment depend on the severity of the infection, the causative bacteria, and the individual's medical history. Over-the-counter or prescription pain relievers may be recommended to alleviate flank pain and discomfort associated with kidney infections. Drinking plenty of fluids, particularly water, helps flush bacteria from the urinary tract and promotes healing. Adequate hydration is essential for supporting kidney function and preventing complications. Resting and avoiding strenuous activity can aid recovery and reduce the strain on the kidneys [2].

Close monitoring of symptoms, including fever and flank pain, is important to ensure the effectiveness of treatment and detect any complications. In severe cases or if complications arise, hospitalization may be necessary for intravenous antibiotics, fluid replacement therapy, and close medical supervision. Practicing good hygiene, including proper genital and perineal care, wiping from front to back after urination or bowel movements, and avoiding douching, can help prevent the spread of bacteria to the urinary tract. Drinking an adequate amount of water each day helps maintain urinary tract health by flushing out bacteria and preventing urinary stasis. Urinating regularly and completely helps prevent the buildup of bacteria in the urinary tract. Avoid delaying urination when the urge arises. Seek prompt medical attention if you experience symptoms of a urinary tract infection, such as painful urination or frequent urination. Early treatment can prevent the infection from spreading to the kidneys. Limit consumption of irritants such as caffeine, alcohol, and spicy foods, which can irritate the bladder and increase the risk of urinary tract infections. Avoiding irritants such as caffeine, alcohol, and spicy foods is commonly recommended to minimize bladder irritation and reduce the risk of urinary tract infections (UTIs) [3].

These substances can exacerbate symptoms in individuals prone to UTIs or those with sensitive bladder conditions. Found in coffee, tea, chocolate, and some sodas, caffeine is a diuretic that increases urine production. While moderate caffeine intake is generally safe for most people, excessive consumption can irritate the bladder and exacerbate urinary urgency and frequency. For individuals prone to UTIs or bladder irritation, reducing caffeine intake can help alleviate symptoms and promote bladder health. Alcohol consumption can irritate the bladder and exacerbate urinary symptoms, particularly in individuals with bladder conditions or a history of UTIs. Alcohol has diuretic properties similar to caffeine, leading to increased urine production and potential bladder irritation. Additionally, certain alcoholic beverages, such as beer and wine, may contain compounds that can irritate the bladder lining, contributing to discomfort and urinary symptoms. Spicy foods, such as chili peppers, hot sauces, and curry dishes, contain compounds like capsaicin that can irritate the bladder and exacerbate urinary symptoms in sensitive individuals. Spicy foods may increase urinary urgency, frequency, and discomfort, making them best avoided or consumed in moderation by individuals prone to UTIs or bladder irritation. By limiting consumption of these irritants, individuals can help reduce the risk of bladder irritation, urinary symptoms, and UTIs. Instead, they can opt for bladder-friendly alternatives and adopt healthy dietary habits to support urinary tract health. Drinking plenty of water, maintaining good hygiene practices, and seeking prompt medical attention for urinary symptoms are also essential for preventing and managing UTIs effectively [4,5].

Conclusion

Kidney infections are a common and potentially serious condition that require prompt diagnosis and treatment to prevent complications and promote recovery. By understanding the causes, symptoms, and treatment options for kidney infections, individuals can take proactive steps to reduce their risk and maintain urinary tract health. Practicing good hygiene, staying hydrated, and seeking timely medical care for urinary tract infections are essential components of kidney infection prevention. With proper management and preventive measures, the incidence of kidney infections can be minimized, improving overall urinary tract health and well-being.

References

1. Kitamura, Asa, Kuniaki Toriyabe, Miki Hagimoto-Akasakaa and Kyoko Hamasaki-Shimada,et al. "Revision of Cytomegalovirus Immunoglobulin M Antibody Titer Cutoff in a Maternal Antibody Screening Program in Japan: A Cohort Comparison Involving a Total of 32,000 Pregnant Women." Viruses 15 (2023): 962.

Google Scholar, Crossref, Indexed at

2. Koyano, Shin, Naoki Inoue, Akira Oka and Hiroyuki Moriuchi, et al. "Screening for congenital cytomegalovirus infection using newborn urine samples collected on filter paper: Feasibility and outcomes from a multicentre study." BMJ Open 1 (2011): e000118.

Google Scholar, Crossref, Indexed at

3. Bauvois, Brigitte and Santos A. Susin. "Revisiting Neutrophil Gelatinase-Associated Lipocalin (NGAL) in cancer: Saint or sinner?" Cancers 10 (2018): 336.

Google Scholar, Crossref, Indexed at

4. Park, Jin-soo, Matan Ben-David, Catriona McKenzie and Charbel Sandroussi. "Cytomegalovirus adrenalitis mimicking adrenal metastasis in an immunocompetent patient." J Surg Case Rep 2022 (2022): rjac122.

Google Scholar, Crossref, Indexed at

5. Gamper, Nikita and Mark S. Shapiro. "Regulation of ion transport proteins by membrane phosphoinositides." Nat Rev Neurosci 8 (2007): 921-934.

Google Scholar, Crossref, Indexed at