Neuro-Ophthalmologic Manifestations and Structures

Isabel Forner^*
*Correspondence: Isabel Forner, Department of Life Sciences, Brunel University London, Kingston Lane, Uxbridge, UK, Email:

Introduction

SLE can affect the eye in several ways, including through ocular surface disease, scleritis, uveitis, retinopathy and neuro-ophthalmologic manifestations. Neuro-ophthalmologic manifestations of SLE occur when the disease affects the visual pathways and structures that control eye movement, such as the optic nerve, extraocular muscles and brainstem. Neuro-ophthalmologic manifestations of SLE can occur at any stage of the disease and can vary in severity. The most common neuro-ophthalmologic manifestations of SLE include. Systemic lupus erythematosus is an autoimmune disease that can affect multiple organ systems, including the eyes. Neuro-ophthalmologic manifestations of SLE are relatively rare but can result in significant visual impairment if not recognized and treated promptly. In this article, we will review the neuro-ophthalmologic manifestations of SLE and their management. Optic neuropathy is a rare but serious complication of SLE that can result in irreversible visual impairment [1].

Description

It occurs when the optic nerve, which carries visual information from the eye to the brain, becomes inflamed or damaged. Symptoms of optic neuropathy can include decreased visual acuity, color vision loss, and visual field defects. SLE can cause inflammation of the cranial nerves, which control eye movement and facial sensation. Cranial nerve palsies can result in double vision, drooping of the eyelid, or facial weakness. Ocular myasthenia gravis is an autoimmune disorder that affects the neuromuscular junctions that control eye movement. It can cause symptoms such as double vision, drooping of the eyelid, and difficulty focusing. Papilledema is a swelling of the optic nerve head that can occur when there is increased pressure within the skull, such as in cases of intracranial hypertension. SLE can cause intracranial hypertension, which can lead to papilledema and visual disturbances. Cerebral ischemia occurs when there is a disruption of blood flow to the brain, which can result in neurological deficits [2].

The management of neuro-ophthalmologic manifestations of SLE requires a multidisciplinary approach, with input from neurologists, rheumatologists and ophthalmologists. Immunosuppressive therapy, such as corticosteroids or immunomodulatory agents, can help to control the underlying autoimmune disease and prevent further damage to the visual pathways. IVIG is a treatment that can be used in cases of severe or refractory neuro-ophthalmologic manifestations of SLE. It works by modulating the immune system and reducing inflammation. Plasmapheresis is a treatment that involves removing plasma from the blood and replacing it with a substitute. It can be used in cases of severe or refractory neuro-ophthalmologic manifestations of SLE to reduce inflammation and remove autoantibodies. In cases of papilledema or other neuro-ophthalmologic manifestations of SLE associated with intracranial hypertension, management may include medications to reduce intracranial pressure [3].

Systemic lupus erythematosus is a chronic autoimmune disease that can affect multiple organ systems, including the eyes. Neuro-ophthalmologic manifestations of SLE are common and can range from mild to severe, affecting both the anterior and posterior segments of the eye. In this article, we will discuss the various neuro-ophthalmologic manifestations of SLE, their clinical presentation, and their management. SLE is a systemic autoimmune disease characterized by the production of autoantibodies that target self-antigens, leading to chronic inflammation and tissue damage. The pathophysiology of neuro-ophthalmologic manifestations of SLE is not fully understood but is believed to involve immune-mediated injury to the blood vessels of the eye and the optic nerve [4].

Neuro-ophthalmologic manifestations of SLE can affect both the anterior and posterior segments of the eye, as well as the optic nerve. Conjunctivitis is inflammation of the conjunctiva, the thin membrane that lines the inside of the eyelids and covers the white part of the eye. It can cause redness, itching, and discharge from the eye. Retinopathy is damage to the blood vessels of the retina, the light-sensitive tissue at the back of the eye. It can cause vision loss, floaters, and blurred vision. SLE can cause cerebral ischemia through vasculitis or thromboembolic events, which can result in visual symptoms such as visual field defects or transient visual loss. Choroidopathy is inflammation of the choroid, a layer of blood vessels and pigment cells that lies between the retina and the sclera. It can cause vision loss, photopsia and floaters [5].

Conclusion

Optic neuropathy is damage to the optic nerve, which carries visual information from the eye to the brain. It can cause vision loss, visual field defects and color vision abnormalities. The clinical presentation of neuroophthalmologic manifestations of SLE can vary depending on the specific manifestation and its severity. Patients may present with symptoms such as eye pain, redness, blurred vision, photophobia, floaters, or vision loss. A comprehensive eye examination is necessary to diagnose and evaluate the severity of these manifestations. Management of neuro-ophthalmologic manifestations of SLE requires a multidisciplinary approach, involving both rheumatologists and ophthalmologists. The primary goals of management are to control inflammation and prevent further damage to the eye.

Acknowledgement

None.

Conflict of Interest

None.

References

1. Pilkington, Karen, Graham Kirkwood, Hagen Rampes and Peter Fisher, et al. "Homeopathy for anxiety and anxiety disorders: A systematic review of the research." Homeopathy 95 (2006): 151-162.

Google Scholar, Crossref, Indexed at

2. Kuzeff, Reinhard M. "Homeopathy, sensation of well-being and CD4 levels: A placebo-controlled, randomized trial." Complement Ther Med 6 (1998): 4-9.

Google Scholar, Crossref, Indexed at

3. PV, Balaji Deekshitulu. "Mental health in women’s and its treatment by tissue remedies." Panacea J Med Sci 5 (2016): 74-81.

Google Scholar, Crossref, Indexed at

4. Sembi, Sundeep, Nicholas Tarrier, Paul O'Neill and Brian Faragher, et al. "Does post‐traumatic stress disorder occur after stroke: A preliminary study." Int J Geriatr Psychiatry 13 (1998): 315-322.

Google Scholar, Crossref, Indexed at

5. Dew, Mary Amanda and Cheryl L. Jacobs. "Psychosocial and socioeconomic issues facing the living kidney donor." Adv Chronic Kidney Dis 19 (2012): 237-243.

Google Scholar, Crossref, Indexed at