Case Report - (2024) Volume 14, Issue 3
Organ transplantation is a life-saving medical procedure for patients with end-stage organ failure. However, despite significant advancements in transplantation medicine, graft rejection remains a major obstacle to successful transplant outcomes. The immune system plays a critical role in recognizing and eliminating foreign tissue, leading to immunological challenges that contribute to graft rejection. This research article aims to review the existing literature on the immunological aspects of transplantation and discuss strategies for enhancing graft survival. By understanding the underlying mechanisms of immune response and developing novel approaches to modulate the immune system, we can pave the way for improved transplantation outcomes and ultimately enhance patients' quality of life.
Organ transplantation has revolutionized modern medicine, providing a lifeline for countless individuals suffering from organ failure. Nevertheless, graft rejection, primarily mediated by the immune system, remains a significant barrier to long-term graft survival. The immune response triggered by the introduction of a foreign graft involves both cellular and humoral mechanisms, resulting in graft damage and eventual rejection. This article aims to provide an overview of the immunological challenges encountered in transplantation and explore potential strategies for mitigating these challenges to achieve enhanced graft survival.
Transplantation Technologies & Research received 223 citations as per Google Scholar report
