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The Impact of Urban Pollution on Aging Skin A Comprehensive Review
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Journal of Dermatology and Dermatologic Diseases

ISSN: 2684-4281

Open Access

Commentry - (2024) Volume 11, Issue 4

The Impact of Urban Pollution on Aging Skin A Comprehensive Review

Sophia Williams*
*Correspondence: Sophia Williams, Department of Dermatology, Stanford University, USA, Email:
1Department of Dermatology, Stanford University, USA

Published: 30-Aug-2024 , DOI: 10.37421/2684-4281.2024.11.472

Abstract

     

Introduction

Urban pollution, driven by industrialization, vehicular emissions, and population density, has become an increasingly prominent environmental challenge. While its effects on respiratory and cardiovascular health are well-documented, the impact of pollution on skin aging is a growing area of concern. Skin, being the body's first line of defense, is directly exposed to various pollutants such as Particulate Matter (PM), Nitrogen Dioxide (NO2), Ozone (O3), and Volatile Organic Compounds (VOCs). These pollutants can cause oxidative stress, inflammation, and DNA damage, all of which accelerate the process of skin aging. Understanding how pollution contributes to skin aging is crucial for developing targeted skincare interventions and public health strategies to mitigate its effects. [1]

Additionally, oxidative stress can impair the skin’s natural barrier function, making it more susceptible to dehydration and irritation. These effects not only contribute to visible signs of aging but also weaken the skin’s ability to repair and regenerate itself over time. [2]

Description

Inflammation is another key factor in the aging process, and urban pollution plays a significant role in triggering chronic low-grade inflammation in the skin. Exposure to pollutants like NO2 and particulate matter activates the skin’s immune cells, leading to the release of pro-inflammatory cytokines. This chronic inflammation accelerates the degradation of collagen and elastin, as well as the production of advanced glycation end-products (AGEs), which further exacerbate skin aging. Inflammation also hinders the skin’s ability to heal and regenerate, making it more vulnerable to environmental stressors. Over time, this leads to a dull complexion, uneven skin tone, and the loss of skin elasticity, further contributing to the visible signs of aging.

Pollution’s effect on skin aging is not limited to oxidative stress and inflammation; it also involves DNA damage. Ultraviolet (UV) radiation from the sun and pollutants such as ozone and VOCs can directly cause DNA mutations in skin cells, triggering premature aging. DNA damage leads to cellular dysfunction, increased cell turnover.

Conclusion

Urban pollution is an increasingly important factor in the accelerated aging of the skin. Through mechanisms such as oxidative stress, chronic inflammation, and DNA damage, pollutants like particulate matter, nitrogen dioxide, and ozone can contribute significantly to premature skin aging. This highlights the need for comprehensive skincare strategies that not only address intrinsic aging but also protect against the harmful effects of environmental pollutants. The development of skincare products with antioxidants, anti-inflammatory agents.

References

  1. Johnpulle, Romany AN, Douglas B. Johnson and Jeffrey A. Sosman. "Molecular targeted therapy approaches for BRAF wild-type melanoma." Curr Oncol Rep 18 (2016): 1-8.
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  3. Gangadhar, Tara C, and Robert H. Vonderheide. "Mitigating the toxic effects of anticancer immunotherapy." Nat Rev Clin Oncol 11 (2014): 91-99
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Google Scholar citation report
Citations: 4

Journal of Dermatology and Dermatologic Diseases received 4 citations as per Google Scholar report

Journal of Dermatology and Dermatologic Diseases peer review process verified at publons

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