Uncommon Metastasis: Head and Neck Carcinoma Spreading to a Percutaneous Endoscopic Gastrostomy Site

Awind Sasus^*
*Correspondence: Awind Sasus, Department of Science and Technology, University of Dhaka, Dhaka, Bangladesh, Email:

Introduction

Uncommon metastasis refers to the spread of cancer from its original site (primary tumor) to a location that is not commonly associated with that type of cancer. In this case, the primary cancer is a head and neck carcinoma, which typically originates in the head or neck region, such as the mouth, throat, or larynx. However, the uncommon metastasis involves the cancer spreading to a Percutaneous Endoscopic Gastrostomy (PEG) site. However, in some adults, this anatomical variant persists .In certain cases, adults with the thyroid in a artery may present unique challenges related to hyperthyroidism. For example, individuals with Graves' disease, a condition characterized by overactive thyroid function, may experience thyroid storm, a severe and potentially life-threatening exacerbation of hyperthyroidism [1,2].

Description

This is a type of cancer that develops in the tissues of the head and neck region. It could include cancers of the mouth, throat (pharynx), voice box (larynx), sinuses, or nasal cavity, among others. Cancer has the ability to spread from its original location to other parts of the body through the bloodstream, lymphatic system, or direct invasion. These secondary sites are known as metastases or metastatic sites. A PEG is a medical procedure in which a feeding tube is inserted directly into the stomach through the abdominal wall. It is commonly used for patients who are unable to consume food or fluids orally and need a way to receive nutrition and medications directly. In this case, the head and neck carcinoma has spread to the site where the percutaneous endoscopic gastrostomy tube has been inserted. This is considered uncommon because head and neck carcinomas do not typically spread to this location. In cases where endoscopic therapies or TAE are unsuccessful or not feasible, surgical resection of the AVM may be necessary. This approach is typically reserved for large, complex, or high-risk lesions. Although no specific, medical treatment exists for gastric AVMs, certain medications such as proton pump inhibitors and iron supplements may be prescribed to manage associated symptoms and complications.

The fact that the cancer has spread to the PEG site is unexpected and unusual, as it is not a typical location for metastasis from head and neck carcinomas. The spread of cancer to this site could have implications for the patient's treatment and management, as it may require additional medical attention and consideration in their overall care plan. Treatment decisions will depend on factors such as the extent of metastasis, the patient's overall health, and the available treatment options. RFA is a newer endoscopic technique that uses thermal energy to ablate abnormal blood vessels. It has shown promise in the treatment of gastric AVMs, particularly smaller lesions. A Percutaneous Endoscopic Gastrostomy (PEG) is a medical procedure used to insert a feeding tube directly into the stomach through a small incision in the abdominal wall. This tube allows for the administration of food, liquids, and medications directly into the stomach, bypassing the mouth and throat. PEG tubes are commonly used for individuals who are unable to eat or drink normally due to medical conditions such as difficulty swallowing, neurological disorders, or certain types of cancer. The PEG procedure is typically performed under endoscopic guidance, using a thin, flexible tube (endoscope) to guide the placement of the feeding tube [3].

Metastasis refers to the spread of cancer cells from their original site, known as the primary tumor, to other parts of the body. These secondary locations where cancer cells settle and grow are called metastatic sites. Cancer cells can spread through the bloodstream or lymphatic system, invading and colonizing distant tissues and organs. Metastasis is a critical stage in cancer progression and can significantly impact treatment options and prognosis. The ability of cancer cells to metastasize is a key factor in the severity and potential lethality of the disease. Effective cancer treatments often target both the primary tumor and any metastatic sites to prevent further spread and manage the disease [4-6].

Conclusion

Overall, these advancements in diagnosis and treatment have expanded the therapeutic options available for gastric AVMs. They offer less invasive approaches, improved success rates in achieving hemostasis, and reduced morbidity and mortality associated with these challenging vascular lesions. However, the choice of treatment depends on factors such as the size and location of the AVM, severity of bleeding and patient characteristics and should be tailored to individual cases..

Acknowledgement

We thank the anonymous reviewers for their constructive criticisms of the manuscript. The support from ROMA (Research Optimization and recovery in the Manufacturing industry), of the Research Council of Norway is highly appreciated by the authors.

Conflict of Interest

The Author declares there is no conflict of interest associated with this manuscript.

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