"Neonatal Sepsis"- Gram Positive & Negative Bacteria's and their Antibiotic Susceptibility in NICU

7^th International Conference on Infectious Diseases: Control and Prevention

May 26-27, 2023 | London, UK

Jibi Thankachan

Tertiary Care Hospital, UK

Scientific Tracks Abstracts: Clin Infect Dis

Abstract :

Back Ground: Neonatal sepsis is one of the most common causes of Neonatal Mortality and Morbidity in developing countries. Its causative bacteria’s and their sensitive patterns are different in each hospitals and regions. The objective of the study was to determine the causation bacteria’s and their pattern of susceptibility to antibiotic s in NICU of a tertiary care center. Material and Methods: The prospective study was carried out at a tertiary care hospital during the period from January 2020 to January 2021. A total of 1712 blood cultures sent from different sites of the patients in NICU during this period. Out of which 1011 cultures came with positive bacterial growth (Includes gram +ve & -ve, Cons and other Recognized pathogens). All cultures were screened by using a micro ESR & Culture and Sensitivity methods. Results: A total of 1011 cultures were found to be positive out of 1712 cultures sent. Out of 1011 positive cultures 450+ are of gram positive organisms and remaining are of positive results with growth. The most common organisms isolated was Staph Epidermidis (68%), followed by Staph Heamolyticus (10%), Staph Hominis(7%), Enterococcus Fecalis(5%). Other Organisms where much less in number which includes Pathogenic Streptococcus, Enterococcus Feacium, Staph Capitis, Bacillus Species etc. There was Incidence of Gram Negative Organisms like E - Coli, Proteus Mirabilis, Serratia Marcescens were also got isolated from Cultures. The Gram Positive Organisms except Streptococcus displayed a high degree of resistance to most Penicillin and Ciprofloxacin and were most time sensitive to Vancomycin, Amikacin and Cefepime. In some cases high incidence of resistance noted with Ampicillin, Gentamicin amongst most Gram Negative Organisms, where in Cefepime, Amikacin and Meropenem were effective in most cases Conclusion: There is an increasing trend of antibiotic resistance to the commonly used front line drugs. Continuo’s surveillance for antibiotic susceptibility is needed to ensure proper empirical therapy.

Biography :

Jibi Thankachan has completed his Bachelor Degree in Nursing from Rajiv Gandhi University, India. After completing the studies he has joined one of the prestigious Hospitals based in USA, Columbia Asia from where he completed his basic Training in Infection Control. he had also completed his advanced training in Infection Control From Columbia Asia Bangalore India. Later he took Specialty training in Surgical Site Infection Prevention from ANCC. Since 2011 he works with King Saud Medical City, Riyadh Saudi Arabia as a Specialist/Senior Preventionist of Infection Control. In 2021 he has completed his Advanced Training in Covid19 Tracing Methodogy from John Hopkins University and also Covid 19 advanced Practices Training from Stanford University Online. He also works a Covid-19 Rapid Response at Central First Health Cluster, MOH, and Riyadh. He has received many Honors and Awards in the field of Infection Control. Many of His Articles were published in one of Middle East largest publications “Clean Middle East” and he is also a frequent writer for Publications in Middle East and KSA.