Brian C Dobson
Performance Edge Systems, New Zealand
Posters-Accepted Abstracts: J Bioproces Biotechniq
Faults in a batch process model of the small intestine create the symptoms of all types of irritable bowel syndrome. The model has three sequential processing sections corresponding to the natural divisions of the small intestine. A brain controller divided into four sub-controllers, each with a unique neurotransmitter, governs it. Each section has a sub-controller to manage transport. Sensors in the walls of the intestine provide input and output goes to the muscles lining the walls of the intestine. The output controls the speed of the food soup, moves it in both directions, mixes it, controls absorption, and transfers it to the next section at the correct speed (slow). The fourth sub-controller manages the addition of bile. It obtains input from the first section of the process via the signaling hormone cholecystokinin and sends output to the muscle that empties the gall bladder. The correct amounts of bile are then added to the first section. The sub-controllers produce output only when input is received. When output is missing, the enteric nervous system applies a default condition. The default condition is normally active when no food is in the intestine. If food is in the intestine and a transport sub-controller fails to provide output, then the default condition moves the food soup to the end of that section. The movement is in one direction only (forward), at a speed dependent on the amount & type of food eaten, and environmental factors affecting the autonomic nervous system. When the default transport speed is �too fast�, irritable bowel syndrome is caused
Email: pesystems@vodafone.net.nz
Journal of Bioprocessing & Biotechniques received 3351 citations as per Google Scholar report