A drug delivery model: 5-fluorouracil intercalated into montmorillonite investigated to the HartreeFock level

2^nd World Chemistry Conference

August 08-10, 2016 Toronto, Canada

John H Summerfield

Missouri Southern State University, USA

Scientific Tracks Abstracts: Chem Sci J

Abstract :

Molecular mechanics calculations, based on equations such as the one below, are used to investigate a colorectal cancer drug, 5-fluorouracil, intercalated into a clay, montmorillonite. This combination is currently being considered as a drug delivery system. The swelling of clays has been studied since the 1930s and is still not fully understood. Spartan� 14 is used for the calculations. Semi-empirical and ab initio basis set scaling is also examined since there are roughly 300 atoms involved in the full model.

Biography :

John H Summerfield has completed his PhD in Physical Chemistry from Oregon State University (1994). His teaching responsibilities include teaching Physics for non-science students, General Chemistry, Physical Chemistry and Organic Chemistry (lab). His specialties/research interests are in computer models of lithium ion batteries and computer models of clays as a drug delivery method.
Email:summerfield-j@mssu.edu