P N De Aza, G J Lugo, P Mazon and L Meseguer-Olmo
Universidad Miguel Hern�¡ndez, Spain
Universidad Cat�³lica San Antonio de Murcia, Spain
Posters & Accepted Abstracts: J Material Sci Eng
The subsystem Nurse�´s A-phase- silcocarnotite within the system Ca3(PO4)2â��Ca2SiO4 was conducted as a preliminary step towards obtaining new biomaterials with controlled microstructures. The subsystem have been investigated, via annealing and quenching in the experimental method, direct observation of phase composition of the resulting ceramics was studied by X-ray diffraction, differential thermal analysis and by scanning electron microscopy with attached wavelength dispersive spectroscopy. The results showed that the sub-system presents an invariant eutectoid point at 1366�±4�°C with a composition of 59.5 wt% Ca3(PO4)2 and 40.5 wt% Ca2SiO4. These results were in disagreement with the previous reported data, which locate the invariant point at 1250�±20�ºC and a composition of 55 wt% Ca3(PO4)2 and 45 wt% Ca2SiO4. In addition, cell attachment test showed that the new eutectoid material supported the mesenchymal stem cells adhesion and spreading, and the cells established close contact with the ceramic after 28 days of culture. These findings indicate that the new ceramic material with eutectoid microstructure of lamellae morphology possesses good bioactivity and biocompatibility and might be a promising bone implant material.
P N De Aza studied Chemistry at the Autonoma University of Madrid and Ceramic at the Santiago de Compostela University, where she received her Doctoral degree in 1995. She completed her Post-doctoral studies at the IRC in Biomaterials at the Queen Mary & Wetsfield College, University of London (U.K.) working on in vitro and in vivo behavior of bioceramics. Currently, she is the Chair of the Materials Science, Optic and Electronic Technology Department, Professor of Materials Science and Metallurgical Engineering and Researcher at the Bioengineering Institute at the Miguel Hernandez de Elche University.
Email: Piedad@umh.es
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