A novel potentiometric ion selective sensor based on piperine for determination of Fe(III) ions

18^th International Conference on Pure and Applied Chemistry

August 31- September 01, 2018 | Toronto, Canada

M C Haputhanthri

University of Colombo, Sri Lanka

Posters & Accepted Abstracts: Med Chem (Los Angeles)

Abstract :

Iron plays a vital role in humans as iron deficiency cause anemia and an overload of iron lead to hemochromatosis. In plants, chlorosis is a common plant disorder that arises as a result of iron deficiency, whilst excess iron leads to toxicity due to the formation of oxygen radicals. As a consequence, there is an imperative need for determination of iron in its ionic form and even in complex matrices. The purpose of this study is to develop a potentiometric solvent polymeric membrane ion-selective electrode using piperine, to be used efficiently in routine analysis of iron. The ISE was calibrated according to the Nernst equation, correlating the Fe(III) concentration with the potential of the ISE measured with respect to an Ag/AgCl reference electrode. Selectivity coefficients were measured using the separate solution method.The electrode exhibits a linear response towards Fe(III) ions in the citrate buffer medium over a concentration range of 1ï?´10-4 to 1 M (detection limit 6.3Ã?10-5 M) with a Nerstian slope of 20.5 mV/decade. The electrode can be successfully used in the pH range 3.15 â?? 7.85 with a lifetime of 3 months. It has fairly a good discriminating ability towards Fe(III) ions among some other metal ions such as K(I), Ca(II), Mg(II), Cu(II), Ba(II), Co(II), Al(III) and Cr(III) with selectivity coefficient of -2.11, -9.02, -10.38,-8.34, -8.12, -8.79, -8.41 and -3.69, respectively. Developed Fe(III) ISE was used to determine Fe(III) concentration in a pharmaceutical sample and the results produced by the sensor were comparable with those obtained using AAS. It proves the fact that, this sensor can be developed into a simple, cost-effective alternate method in determining Fe3+ ion concentrations in biological and analytical samples.

Biography :

E-mail: madhuhaputhanthrixxx@gmail.com