A X-ray therapy of skin cancer and benign skin lesions

JOINT EVENT: 4^th International Conference and Exhibition on Medical Physics and Biophysics & 2^nd International Conference on Nuclear Medicine & Radiation Therapy

July 27-28, 2017 Rome, Italy

Hans Christian Wulf

Bispebjerg Hospital, Denmark

Posters & Accepted Abstracts: J Nucl Med Radiat Ther

Abstract :

X-ray therapy of skin lesions has until recently been used for treatment of basal cell carcinoma and squamous cell carcinoma as an alternative to surgery. For 100 years, X-rays have also been used to treat a great variety of chronic, benign skin diseases. A revival of this therapy method is now seen alongside new equipment suitable for low penetration x-ray treatment. Traditionally, tumors are treated with a total dose of 40-50 Gy, administered in approximately 10 fractions. The penetration of the X-rays is normally chosen so that 50% of the surface dose is present in the bottom of the tumor, and 50% will penetrate into the underlying, healthy skin, so an estimate of tumor thickness must be made. The half-value-layer (HVL) depends on the equipment; examples are given in the Figure 1. Other skin tumors, such as Kaposi�s sarcomas, are very sensitive to x-ray therapy and may be treated with 8-12 Gy in 2-3 fractions.Success rate is about 93% for primary tumors. Chronic skin diseases which cannot be controlled sufficiently by other treatments may also be treated with x-ray therapy, such as eczema, psoriasis, Darier�s disease, Hailey-Hailey disease, actinic keratoses. When treating inflammatory chronic diseases it is important not to administer very high cumulative doses over several years as it has been done in the past. Malign tumors such as mycosis fungoides, Bowen�s disease and Paget�s disease are also treatable by x-ray. Clinical examples will be presented.

Biography :

Email: h.wulf@regionh.dk